Peptide library

Stimulates growth | Treats growth hormone deficiency

HGH (somatropin) is recombinant human growth hormone, FDA-approved for pediatric and adult GH deficiency and several wasting and short-stature conditions; widely studied for body composition off-label.

GLP-1 Agonist | Type 2 Diabetes and Obesity Management

Semaglutide is a synthetic analog of glucagon-like peptide-1 (GLP-1), a hormone involved in glucose metabolism and appetite regulation. As a GLP-1 receptor agonist, semaglutide enhances insulin secretion in response to elevated blood glucose levels, suppresses glucagon secretion, and slows gastric emptying, leading to improved glycemic control. Additionally, it promotes satiety, contributing to weight loss, which has made it a focus of research for managing both type 2 diabetes and obesity.

Antioxidant | Supports immune function

Glutathione (GSH) is a tripeptide composed of glutamine, cysteine, and glycine, recognized as the body's primary intracellular antioxidant. It plays a critical role in maintaining redox balance, detoxifying harmful compounds, and supporting immune function. GSH is also involved in various cellular processes, including the regulation of cell proliferation and apoptosis, making it essential for overall cellular health and function.

LHCGR Agonist | Fertility support and testosterone stimulation

HCG (Human Chorionic Gonadotropin) is a glycoprotein hormone produced by the placenta during pregnancy, structurally similar to luteinizing hormone (LH). It plays a crucial role in regulating reproductive processes in both men and women. In clinical settings, HCG is primarily used to stimulate endogenous testosterone production in men with hypogonadism and to support fertility treatments in women, particularly in assisted reproductive technologies such as in vitro fertilization (IVF).

Metabolic | Energy production and cellular repair

NAD+ (Nicotinamide adenine dinucleotide) is a crucial coenzyme involved in various metabolic processes, including energy production and cellular repair mechanisms. Recent research highlights its potential roles in protecting against oxidative stress and enhancing therapeutic efficacy in certain cancer treatments.

Neuropeptide | Social bonding and emotional regulation

Oxytocin is a neuropeptide synthesized in the hypothalamus and released by the posterior pituitary gland. It plays a significant role in various physiological and behavioral processes, including social bonding, reproductive behaviors, emotional regulation, childbirth, and lactation. The mechanisms of action of oxytocin involve its binding to specific receptors in the brain and peripheral tissues, influencing neural circuits associated with social cognition, attachment, and stress response.

Neuropeptide | Gastrointestinal disorders

Vasoactive Intestinal Peptide | Neuropeptide

Erythropoiesis | Anemia treatment

Erythropoietin (EPO) is a glycoprotein hormone primarily produced by the kidneys in response to hypoxia. Its main function is to stimulate the production of red blood cells (erythropoiesis) in the bone marrow by binding to erythropoietin receptors (EPOR) on erythroid progenitor cells. This interaction activates various intracellular signaling pathways, including the JAK2/STAT5 pathway, which promotes cell survival, proliferation, and differentiation of erythroid progenitors.

Mitochondrial protection | Heart and neuro health

SS-31, also known as Elamipretide, is a peptide that has garnered attention for its potential role in mitochondrial protection and its implications in various health conditions, particularly those involving oxidative stress and mitochondrial dysfunction.

Antimicrobial | Immune response

LL-37 is a human cathelicidin antimicrobial peptide that plays a crucial role in the innate immune response. It is produced by various cells, including epithelial cells and neutrophils, and exhibits a broad spectrum of biological activities, including antimicrobial, immunomodulatory, and wound healing properties. LL-37 interacts with a variety of pathogens, including bacteria, viruses, and fungi, contributing to the host's defense mechanisms.

Vasopressor | Diabetes insipidus treatment

Research peptide discovered via AI researcher. peptide-based therapeutic

PTH1R Activation | Osteoporosis Treatment

Abaloparatide (Tymlos) is a synthetic PTHrP analog and FDA-approved anabolic agent for osteoporosis, building bone via selective PTH1R activation.

ERR Agonist | Metabolic Modulator

Synthetic Pan-ERR Agonist | Exercise Mimetic & Metabolic Modulator

Neuroprotection | Nerve regeneration

ARA 290, also known as a peptide derived from the erythropoietin (EPO) molecule, has garnered attention for its potential therapeutic applications, particularly in the context of nerve regeneration and protection. The peptide is designed to mimic some of the beneficial effects of EPO without eliciting the same erythropoietic activity, which can lead to unwanted side effects such as increased blood viscosity and hypertension.

Somatostatin analog | Treats acromegaly and tumors

Research peptide discovered via AI researcher. peptide-based therapeutic

GLP-1 Agonist | Type 2 Diabetes and Obesity

Orforglipron (LY-3502970) is an investigational oral small-molecule GLP-1 receptor agonist studied for type 2 diabetes and obesity, offering pill-based dosing without injection.

Modulation of endothelial function | Vascular health

PE 22-28 is a peptide that has attracted interest for its potential roles in vascular health and metabolic conditions, particularly in the context of gestational diabetes and placental function. The peptide is derived from the sequence of the human protein, and its mechanism of action is thought to involve modulation of endothelial function and inflammatory responses, which are critical in maintaining vascular integrity and metabolic homeostasis.

Triple Agonist | Weight Loss & Diabetes

Triple GLP-1/GIP/Glucagon Agonist | Weight Loss & Diabetes

NPR2 Activation | Growth Disorders

Research peptide discovered via AI researcher. peptide-based therapeutic

GnRH Agonist | Prostate cancer treatment

Leuprorelin is a synthetic analog of gonadotropin-releasing hormone (GnRH) that functions primarily as a GnRH agonist. Its mechanism of action involves the downregulation of gonadotropin secretion from the pituitary gland, which subsequently leads to decreased levels of sex hormones such as testosterone and estrogen. This property makes leuprorelin particularly useful in the treatment of hormone-sensitive conditions, including prostate cancer, endometriosis, and precocious puberty.

Dual Agonist | Obesity and metabolic disorders

Survodutide (BI 456906) is an investigational dual agonist that targets both glucagon-like peptide-1 (GLP-1) and glucagon receptors. This peptide is primarily being studied for its potential in treating obesity and metabolic dysfunction-associated steatotic liver disease (MASLD). The dual action of Survodutide is designed to enhance weight loss while also improving glycemic control, which is particularly relevant for individuals with type 2 diabetes and related metabolic disorders.

Metabolic regulation | Male fertility

MOTS-C is a mitochondrial-derived peptide that has garnered attention for its potential roles in metabolic regulation and cellular stress responses. Emerging research suggests it may have implications in various health conditions, including cardiovascular diseases and placental function.

Somatostatin analog | Management of acromegaly

Research peptide discovered via AI researcher. peptide-based therapeutic

Copper-binding | Skin and wound healing

Copper-binding tripeptide widely used in skin, hair, and wound-healing contexts, with systemic effects explored in research.

GLP-1/glucagon agonist | Weight loss and diabetes

Mazdutide (IBI362) is an investigational dual GLP-1/glucagon receptor agonist studied for weight loss and type 2 diabetes, combining appetite suppression with increased energy expenditure.

Activation | Muscle repair and recovery

MGF (Mechano Growth Factor) is a splice variant of Insulin-like Growth Factor 1 (IGF-1) that is primarily expressed in muscle tissue in response to mechanical overload or injury. It plays a crucial role in muscle repair and regeneration by activating satellite cells, which are essential for muscle growth and recovery. MGF is thought to enhance muscle hypertrophy and improve recovery from exercise-induced damage through its anabolic effects on muscle cells.

GIP/GLP-1 Agonist | Type 2 Diabetes and Obesity

Tirzepatide is a novel dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist that has been investigated for its potential in managing type 2 diabetes and obesity. Its unique mechanism of action aims to enhance glycemic control and promote weight loss.

CNS Action | Sleep Regulation

Delta Sleep-Inducing Peptide (DSIP) is a neuropeptide that has garnered attention for its potential roles in sleep regulation, stress modulation, and pain management. It is primarily known for promoting sleep and improving sleep quality, which is critical for overall health. DSIP has been shown to influence various physiological processes, including the modulation of neurotransmitter release and the regulation of hormonal systems, particularly those involved in stress responses.

KISS1R Activation | Fertility Regulation

Kisspeptin (KP-10) is a decapeptide derived from the KISS1 gene, known for its role in the regulation of the hypothalamic-pituitary-gonadal (HPG) axis. It primarily functions by activating the KISS1 receptor (KISS1R), which stimulates the release of gonadotropin-releasing hormone (GnRH). This cascade is crucial for the regulation of reproductive hormones, including luteinizing hormone (LH) and follicle-stimulating hormone (FSH), thereby influencing fertility and reproductive health.

Ghrelin receptor agonist | Muscle mass enhancement

MK-677, also known as Ibutamoren, is a growth hormone secretagogue that has garnered attention for its potential effects on muscle mass and body composition. Research is ongoing to better understand its mechanisms and applications in various contexts, including its detection in biological samples.

Oxytocin Agonist | Prevents Postpartum Hemorrhage

Carbetocin is a synthetic analog of oxytocin, primarily used for the prevention of postpartum hemorrhage (PPH). It acts as a selective agonist at the oxytocin receptor, promoting uterine contractions and facilitating the expulsion of the placenta, which can significantly reduce the risk of excessive bleeding following childbirth. Unlike oxytocin, carbetocin has a longer half-life, allowing for sustained action with a single administration, which may enhance its efficacy in clinical settings.

GnRH Agonist | Prostate cancer treatment

Research peptide discovered via AI researcher. peptide-based therapeutic

Fatty acid transport | Metabolic health

L-Carnitine (levocarnitine) is an amino acid derivative that shuttles long-chain fatty acids into mitochondria for energy production, studied for metabolic, cardiovascular, and exercise performance applications.

GLP-1 receptor agonist | Diabetes management

Liraglutide is a synthetic analog of human glucagon-like peptide-1 (GLP-1), a hormone that plays a crucial role in glucose metabolism and appetite regulation. It acts as a GLP-1 receptor agonist, stimulating insulin secretion in response to elevated blood glucose levels while suppressing glucagon release, which helps lower blood sugar levels. Additionally, liraglutide slows gastric emptying and promotes satiety, contributing to weight loss in individuals with obesity or type 2 diabetes.

Neuroprotection | Cognitive decline

P21 (P021) is a CNTF-derived neurogenic peptide researched preclinically for cognitive decline, tau pathology, and BDNF-mediated neuroprotection. Research-use only with no human trial data.

Radioligand therapy | Prostate cancer treatment

Research peptide discovered via AI researcher. research peptide

Stimulates LH and FSH | Reproductive health

Gonadorelin is synthetic GnRH, a decapeptide that stimulates pituitary release of LH and FSH in pulsatile fashion — used diagnostically and to support the reproductive hormone axis.

GLP-1 Agonist | Type 2 Diabetes Management

Research peptide discovered via AI researcher. peptide-based therapeutic

Muscle contraction inhibition | Skin rejuvenation

Snap-8, a synthetic peptide, is often explored for its potential anti-aging and skin-rejuvenating properties, particularly in cosmetic applications. Research into its efficacy and mechanisms of action is ongoing, with a focus on its ability to reduce the appearance of fine lines and wrinkles.

GLP-1 Agonist | Type 2 Diabetes Management

Exenatide is a synthetic peptide that mimics the action of glucagon-like peptide-1 (GLP-1), a hormone involved in glucose metabolism. It functions primarily as a GLP-1 receptor agonist, promoting insulin secretion in response to elevated blood glucose levels, inhibiting glucagon release, and slowing gastric emptying. These mechanisms contribute to improved glycemic control in patients with type 2 diabetes and may also aid in weight management due to its appetite-suppressing effects.

Gonadotropin | Ovulation induction in IVF

HMG (Human Menopausal Gonadotropin) is a urine-derived injectable containing FSH and LH activity, used clinically to drive ovulation in IVF cycles and restore spermatogenesis in hypogonadotropic men.

Localized muscle growth | Tissue repair

IGF-1 DES (Des(1-3) IGF-1) is a truncated IGF-1 analog studied for localized muscle growth and tissue repair, with reduced IGFBP binding and higher local receptor activity.

Immunomodulation | Wound healing

KPV is a tripeptide composed of lysine, proline, and valine, which has been studied for its potential immunomodulatory and wound healing properties. Its mechanism of action is thought to involve the modulation of inflammatory responses, potentially through the inhibition of pro-inflammatory cytokines and promotion of anti-inflammatory pathways. KPV may also enhance the healing process by promoting angiogenesis and fibroblast proliferation, which are critical for tissue repair.

Melanocortin Agonist | Sexual Dysfunction

PT-141 (Bremelanotide) is a synthetic peptide that acts as a melanocortin receptor agonist, primarily investigated for its potential to treat sexual dysfunction, particularly in women experiencing hypoactive sexual desire disorder. Its mechanism of action involves the modulation of pathways related to sexual arousal and desire.

Neuroprotection | Anxiolytic and cognitive enhancement

Selank is a synthetic peptide derived from the naturally occurring peptide tuftsin, primarily studied for its potential anxiolytic and cognitive-enhancing properties. Research into Selank has focused on its effects on neuroprotection, stress response, and cognitive function, although further studies are needed to fully understand its mechanisms and therapeutic applications.

Inhibition | Weight loss and metabolic regulation

Tesofensine is a synthetic compound that was initially developed as an antidepressant but has garnered interest for its potential role in weight loss and metabolic regulation. Its mechanism of action involves the inhibition of the reuptake of neurotransmitters such as serotonin, norepinephrine, and dopamine, which may lead to reduced appetite and increased energy expenditure. By modulating these neurotransmitters, tesofensine may help in regulating energy balance and body weight.

Immune modulation | Infections and inflammatory diseases

Thymosin Alpha-1 (Tα1) is a peptide that plays a crucial role in modulating immune responses and has been investigated for its potential therapeutic applications in various conditions, including infections and inflammatory diseases.

Neuroprotective | Stroke recovery and dementia

Cerebrolysin is a porcine brain-derived peptide preparation studied for stroke recovery, dementia, and TBI, with proposed neurotrophic and neuroprotective effects on the central nervous system.

Amylin receptor agonist | Obesity treatment

Eloralintide is a selective amylin receptor agonist that has been investigated for its potential role in the treatment of obesity. The mechanism of action involves the activation of amylin receptors, which are implicated in regulating appetite and glucose metabolism. By mimicking the effects of the naturally occurring hormone amylin, Eloralintide may help reduce food intake and promote weight loss through central nervous system pathways that influence satiety and energy expenditure.

Antidiuretic | Diabetes insipidus, nocturnal enuresis

Desmopressin is a synthetic analog of arginine vasopressin (AVP), a hormone that plays a critical role in regulating water retention in the body. It primarily acts on the kidneys, promoting water reabsorption in the collecting ducts, which leads to decreased urine output. Desmopressin is commonly used in the treatment of conditions such as diabetes insipidus and nocturnal enuresis due to its antidiuretic properties.

GLP-1 Agonist | Type 2 Diabetes Management

Dulaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist that is used primarily for the treatment of type 2 diabetes. It mimics the action of the endogenous GLP-1 hormone, which is involved in glucose metabolism. The mechanism of action includes stimulating insulin secretion in response to elevated blood glucose levels, inhibiting glucagon release, and slowing gastric emptying, which collectively contribute to improved glycemic control and potential weight loss.

Mitochondrial function | Longevity

Humanin is a mitochondria-derived peptide that has garnered attention for its potential roles in cellular health and longevity. It is encoded by the mitochondrial genome and is involved in various cellular processes, including the regulation of apoptosis, inflammation, and oxidative stress. The peptide has been implicated in protective mechanisms against neurodegenerative diseases and metabolic disorders, suggesting its potential as a therapeutic agent in these conditions.

Collagen stimulation | Skin rejuvenation

Matrixyl, a peptide known for its potential skin-rejuvenating properties, is often incorporated into cosmetic formulations aimed at reducing the appearance of wrinkles and improving skin texture. Research continues to explore its mechanisms of action and effectiveness in various applications, particularly in dermal health and aesthetics.

p53 Disruption | Cancer Treatment

PNC-27 is a peptide designed to disrupt the interaction between the tumor suppressor protein p53 and its negative regulator, HDM2 (human double minute 2). This interaction is crucial in the regulation of cell cycle and apoptosis, as p53 is a key player in preventing cancer cell proliferation. By inhibiting the p53-HDM2 interaction, PNC-27 aims to restore the function of p53, thereby promoting apoptosis in cancer cells and potentially reducing tumor growth.

Amylin analog | Obesity and type 2 diabetes

Cagrilintide (AM833) is a long-acting amylin analog investigated for once-weekly subcutaneous use in obesity and type 2 diabetes, most notably combined with semaglutide as CagriSema.

GnRH Antagonist | Prostate cancer treatment

Degarelix is a synthetic peptide that functions as a gonadotropin-releasing hormone (GnRH) antagonist. By competitively inhibiting GnRH receptors in the pituitary gland, degarelix reduces the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), leading to decreased testosterone production in the testes. This mechanism is particularly beneficial in the treatment of hormone-sensitive conditions such as prostate cancer, where testosterone can promote tumor growth.

GHRH Mimetic | Growth Hormone Deficiency

Sermorelin is a synthetic peptide that acts as a growth hormone-releasing hormone (GHRH) analog, primarily stimulating the pituitary gland to enhance the secretion of endogenous growth hormone (GH). The mechanism of action involves binding to GHRH receptors on pituitary somatotrophs, leading to increased production and release of GH. This endogenous GH then exerts various physiological effects, including promoting growth, metabolism, and tissue repair.

Bone-Building | Osteoporosis treatment

PTH(1-34) | Bone-Building Anabolic Peptide

Immunomodulatory | Immune function regulation

FTS | Zinc-Dependent Thymic Nonapeptide

Ghrelin receptor activation | Muscle growth

GHRP-6 (Growth Hormone Releasing Peptide-6) is a synthetic hexapeptide that acts as a growth hormone secretagogue (GHS). It primarily stimulates the release of growth hormone (GH) from the anterior pituitary gland through the activation of the ghrelin receptor (GHS-R). This mechanism is believed to be mediated by the stimulation of the hypothalamus, which subsequently promotes the release of growth hormone-releasing hormone (GHRH) and inhibits somatostatin, thereby enhancing GH secretion.

Somatostatin analog | Acromegaly management

Research peptide discovered via AI researcher. peptide-based therapeutic

MC4R Agonist | Obesity Treatment

Research peptide discovered via AI researcher. peptide-based therapeutic

Neuroinhibition | Aesthetic

Argireline, or Acetyl Hexapeptide-3, is a synthetic peptide that has gained attention in cosmetic formulations due to its potential anti-aging effects. It is often compared to botulinum toxin, as it is believed to reduce the appearance of fine lines and wrinkles through a mechanism that involves inhibiting the release of neurotransmitters that cause muscle contraction. This action may lead to a temporary relaxation of facial muscles, thereby minimizing the formation of expression lines.

IGF-1 receptor agonist | Muscle growth

IGF-1 LR3 is a long-acting synthetic IGF-1 analog with reduced binding-protein affinity, used as a research-grade IGF-1 receptor agonist studied for muscle and tissue growth.

Melanogenesis | Photoprotection for light-sensitive skin

Melanotan I (afamelanotide) is a synthetic alpha-MSH analog and melanocortin receptor agonist studied primarily for photoprotection in light-sensitive skin disorders.

Modulating appetite | Metabolic disorders

Research peptide discovered via AI researcher. research peptide

Neuroprotection | Cognitive enhancement

Adamax is a synthetic next-generation derivative of the Semax neuropeptide, researched for cognitive enhancement, neuroprotection, and BDNF/NGF modulation, with limited human data outside the Semax family.

Telomerase activation | Longevity

Epitalon, also known as Epithalon or Epithalamin, is a synthetic tetrapeptide derived from the pineal gland that has garnered interest for its potential effects on aging and various physiological processes. Research has explored its bioactive properties, particularly in relation to reproductive health and the aging of the pineal gland.

Myostatin inhibition | Muscle growth regulation

Follistatin-344 is a glycoprotein that plays a significant role in muscle growth and development by acting as an inhibitor of myostatin, a protein that negatively regulates muscle mass. By binding to myostatin and preventing its action, follistatin-344 promotes muscle hypertrophy and has garnered interest for its potential therapeutic applications in muscle wasting disorders, regenerative medicine, and other conditions related to muscle atrophy.

NNMT Inhibition | Weight management

Research-peptide often discussed for body recomposition: weight-loss–focused with muscle preservation, cholesterol and inflammation effects.

GLP-1 Agonist | Type 2 Diabetes Management

Albiglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist that was developed for the treatment of type 2 diabetes mellitus (T2DM). It functions by mimicking the action of the endogenous GLP-1 hormone, which is involved in glucose metabolism. Albiglutide enhances insulin secretion in response to elevated blood glucose levels, suppresses glucagon secretion, slows gastric emptying, and promotes satiety, thereby contributing to improved glycemic control and weight management.

Metabolic | Glucose metabolism and energy homeostasis

Research peptide discovered via AI researcher. research peptide

Angiogenesis | Soft tissue repair

BPC-157, or Body Protective Compound-157, is a synthetic peptide derived from a protein found in human gastric juice. It has gained attention for its potential roles in soft-tissue repair, gastrointestinal (GI) support, and modulation of inflammation. The peptide is believed to exert its effects through various mechanisms, including the promotion of angiogenesis, modulation of growth factors, and reduction of oxidative stress and inflammation.

MC1R Agonist | Skin pigmentation

Melanotan II is a synthetic analog of the naturally occurring peptide hormone alpha-melanocyte-stimulating hormone (α-MSH), primarily studied for its effects on skin pigmentation and potential therapeutic applications. Research has also explored its impact on mood and stress responses, though caution is advised due to potential side effects and safety concerns.

Neurotrophic | Parkinson's disease

DNSP-11 is an 11-amino-acid peptide derived from the GDNF pro-region, studied preclinically for its neurotrophic effects on dopaminergic neurons in Parkinson's disease research models.

Immune modulation | Autoimmune diseases

Evuzamitide is a peptide-based therapeutic agent that was developed using artificial intelligence methodologies. Its primary aim is to exploit the unique properties of peptides for various therapeutic applications, although the specific mechanisms of action are still under investigation. Current research suggests that Evuzamitide may interact with multiple biological pathways, but detailed studies elucidating these interactions are ongoing.

Melanocortin receptor agonist | Skin pigmentation

Melanotan 1, also known as afamelanotide, is a synthetic analog of α-melanocyte-stimulating hormone (α-MSH) that primarily acts as a melanocortin receptor agonist. It has been investigated for its potential applications in enhancing skin pigmentation and its role in various therapeutic contexts, including neuroprotection and cancer research.

GHRH analog | Reduces visceral fat in HIV lipodystrophy

Tesamorelin is a synthetic peptide that acts as a growth hormone-releasing hormone (GHRH) analog. It is primarily investigated for its potential to reduce visceral fat in individuals with HIV-associated lipodystrophy, a condition characterized by abnormal fat distribution often exacerbated by antiretroviral therapy. Tesamorelin stimulates the release of endogenous growth hormone, which in turn promotes lipolysis and reduces visceral adipose tissue (VAT) accumulation.

Lipolysis | Fat loss

A GH-fragment–derived peptide primarily discussed for fat loss and body-composition change, sometimes with cartilage and joint-repair context.

Protonophore uncoupler | Metabolic dysfunction

BAM-15 is a mitochondrial protonophore uncoupler studied preclinically for obesity, insulin resistance, and metabolic dysfunction by increasing energy expenditure without raising heart rate.

Vasopressin analog | Managing fluid balance

Research peptide discovered via AI researcher. peptide-based therapeutic

Neuroprotective | Cognitive enhancement

Semax is a synthetic peptide derived from the adrenocorticotropic hormone (ACTH) that has been investigated for its potential neuroprotective and cognitive-enhancing effects. Research suggests that Semax may influence various biological pathways, including neuroinflammation and intracellular calcium dynamics.

Immune Modulator | Thymic Peptide Bioregulator

Thymic Peptide Bioregulator | Immune Modulator

Pro-apoptotic | Obesity

Adipotide (Prohibitin-TP01) is an experimental peptidomimetic that targets prohibitin on white adipose vasculature to trigger fat-supply regression, studied preclinically for obesity.

Melanocortin activation | Skin pigmentation

Research peptide discovered via AI researcher. peptide-based therapeutic

AMPK activator | Metabolic efficiency

AICAR (Acadesine) is a small-molecule compound that functions as an activator of AMP-activated protein kinase (AMPK), a crucial regulator of cellular energy homeostasis. By mimicking AMP, AICAR promotes a shift in cellular metabolism toward energy-producing pathways, thereby enhancing metabolic efficiency. The activation of AMPK by AICAR has been associated with various physiological effects, including improved endurance, metabolic adaptation, and cardioprotective properties.

Modulates IGF-1 | Neuroprotection

Cyclic Glycine-Proline (cGP) is a cyclic dipeptide that is derived from the peptide insulin-like growth factor 1 (IGF-1). It is characterized by its unique cyclic structure, which is believed to enhance its stability and bioavailability compared to linear peptides. cGP is primarily studied for its potential neuroprotective effects and its role in modulating cognitive aging, making it a subject of interest in neurobiology and gerontology.

Neuroprotection | Cognitive enhancement

Experimental nootropic peptide investigated for neuroprotection, memory, and stroke/spinal-cord recovery.

GnRH Agonist | Reproductive health

Research peptide discovered via AI researcher. peptide analogue

GHRH analogue | GH/IGF-1 modulation

GHRH analogue used in research contexts for GH/IGF-1 modulation, muscle and bone density, sleep, and recovery.

FGFR Agonist | Neuroprotection

FGL is a synthetic 15-amino-acid peptide derived from the NCAM FG loop, studied preclinically as an FGFR agonist for synaptic plasticity, memory, and neuroprotection.

Prolactin receptor targeting | Androgenetic alopecia

ABS-201 is an investigational IgG1 monoclonal antibody that targets the prolactin receptor (PRLR), currently under clinical development for androgenetic alopecia (AGA). The mechanism of action involves the inhibition of PRLR signaling, which is thought to play a role in hair follicle biology and hair growth regulation. By blocking this receptor, ABS-201 may potentially alter the hair growth cycle and promote hair regrowth in individuals affected by AGA.

Ghrelin-receptor agonist | Growth hormone stimulation

GHRP-2 (pralmorelin) is a synthetic hexapeptide and ghrelin-receptor agonist studied as a growth hormone secretagogue, used clinically as a diagnostic agent and investigationally for GH-related research.

GHRH analog | Growth hormone secretion

CJC-1295 with DAC is a long-acting GHRH analog bound to serum albumin, studied as an investigational growth hormone secretagogue with a multi-day half-life and sustained IGF-1 elevation.

Mitochondrial stabilization | Mitochondrial dysfunction

Research peptide discovered via AI researcher. peptide-based therapeutic

Amylin receptor agonist | Diabetes management

Research peptide discovered via AI researcher. peptide-based therapeutic

Cell migration | Tissue repair and regeneration

TB-500, a synthetic derivative of thymosin beta-4, is a peptide that has garnered attention for its potential role in tissue repair and regeneration. Research into TB-500 is ongoing, particularly regarding its applications in equine medicine and its implications in doping control.

Healing | Tissue repair and regeneration

Thymosin Beta-4 Active Fragment | Healing Peptide

Immune Bioregulator | Thymus Function Enhancement

EW Dipeptide | Thymus Immune Bioregulator

Myostatin decoy | Muscle-wasting conditions

ACE-031, also known as ACVR2B-Fc, is an investigational fusion protein designed to act as a decoy receptor for myostatin, a negative regulator of muscle growth. By binding to myostatin, ACE-031 prevents it from interacting with its natural receptor, thereby promoting muscle hypertrophy and regeneration. This mechanism of action positions ACE-031 as a potential therapeutic agent for muscle-wasting conditions, including Duchenne muscular dystrophy (DMD) and other myopathies.

Vasodilation | Anti-fibrotic

B7-33 is a single-chain peptide analog of relaxin-2 designed to retain anti-fibrotic and vasodilatory signaling while simplifying synthesis. It is investigational and research-use only.

GHRH analog | Growth hormone stimulation

CJC-1295 without DAC (Modified GRF 1-29) is a short-acting GHRH analog studied for its ability to stimulate pulsatile growth hormone release from the pituitary.

GHS-R Agonism | Muscle Wasting

Hexarelin is a synthetic hexapeptide that belongs to the growth hormone secretagogue (GHS) class, known for its ability to stimulate growth hormone release from the pituitary gland. It has been investigated for its potential therapeutic applications in various conditions, including muscle wasting and age-related decline in growth hormone levels.

Bioregulator | Pancreatic endocrine support

Pancragen (KEDW) is a synthetic tetrapeptide bioregulator studied for pancreatic endocrine support, glucose-insulin modulation, and longevity applications in preclinical and small human studies.

GLP-1 Activation | Metabolic Regulation

Research peptide discovered via AI researcher. peptide-based therapeutic

Stimulates GLP-1 secretion | Appetite regulation

GLP-1 blends refer to combinations of glucagon-like peptide-1 (GLP-1) analogs or related compounds that may enhance the secretion of this hormone, which plays a critical role in glucose metabolism and appetite regulation. Recent research has explored various natural extracts and dietary components that may influence GLP-1 secretion and its physiological effects.

Receptor Interaction | Metabolic Regulation

Research peptide discovered via AI researcher. research peptide

Gene expression modulation | Liver support

Ovagen (EDL) is a Khavinson-family tripeptide bioregulator researched for liver and gastrointestinal tissue support, proposed to act via gene-expression modulation in hepatocytes and enterocytes.

GLP-2 analog | Short Bowel Syndrome

Research peptide discovered via AI researcher. peptide-based therapeutic

GLP-1 Agonist | Type 2 Diabetes Treatment

Research peptide discovered via AI researcher. peptide-based therapeutic

Neurotrophic | Cognitive enhancement

IllumiNeuro Protocol is a cognitive enhancement blend consisting of four peptides, primarily focusing on nootropic and neurotrophic effects. The peptides included in this protocol are Selank and Semax, which have been studied for their potential to improve memory, focus, and neuroprotection. The mechanisms of action for these peptides involve modulation of neurotransmitter systems, neuroinflammation, and neurogenesis, which may contribute to their cognitive-enhancing properties.

Ghrelin Agonist | Growth Hormone Release

Ipamorelin is a synthetic peptide that acts as a selective agonist of the growth hormone secretagogue receptor, primarily stimulating growth hormone release. Its potential therapeutic applications are being explored in various contexts, including weight management and pain modulation.

Immune modulation | Tissue regeneration

Thymalin, also known as Thimulin, is a peptide derived from the thymus gland that is believed to play a role in immune modulation and tissue regeneration. Research has explored its potential applications in enhancing reparative processes and influencing immune cell activity.

Tissue repair | Wound healing

Thymosin Beta-4 (Tβ4) is a 43-amino acid peptide that plays a significant role in tissue repair and regeneration. It is involved in various biological processes, including cell migration, angiogenesis, and inflammation modulation. Tβ4 has been shown to promote wound healing by enhancing keratinocyte migration and proliferation, as well as by facilitating the formation of new blood vessels, which are crucial for tissue repair.

GnRH Agonist | Hormone regulation

Research peptide discovered via AI researcher. peptide analogue

Bioregulator | Bladder & Urinary Tract Health

ED Dipeptide | Bladder & Urinary Tract Bioregulator

Growth Hormone Secretagogue | Muscle Growth

Research peptide discovered via AI researcher. research peptide

GLP-1 Agonist | Type 2 Diabetes Management

Research peptide discovered via AI researcher. research peptide

Lipid metabolism | Fat loss

HGH Fragment 176-191, a peptide derived from the C-terminus of human growth hormone (HGH), has been primarily researched for its potential effects on fat loss and metabolic regulation. This peptide is believed to mimic some of the metabolic effects of HGH without the associated growth-promoting side effects. The mechanism of action is thought to involve the modulation of lipid metabolism and glucose uptake in adipocytes, which may contribute to its fat loss properties.

Neuroprotection | Cognitive enhancement

NA Semax Amidate is a modified heptapeptide analog of Semax (ACTH 4-10 fragment) studied for cognitive enhancement, neuroprotection, and BDNF/NGF modulation in preclinical research.

Dual agonist | Metabolic regulation

Research peptide discovered via AI researcher. research peptide

Thymus Immune Bioregulator | Immune modulation

Vilon (KE), a dipeptide, is classified as a thymus immune bioregulator. Its primary mechanism of action involves modulation of immune responses, particularly through the influence on monocyte and macrophage activity. Research indicates that Vilon can regulate proliferative activity and inflammatory pathways in immune cells, which may have implications for conditions characterized by immune dysregulation.

Gene expression modulation | Cardiovascular support

Cardiogen (AEDR) is a short synthetic peptide bioregulator researched primarily for cardiovascular tissue support, vascular function, and age-related cardiac decline in preclinical models.

Gene modulation | Cartilage support

Cartalax (AED peptide) is a synthetic tripeptide developed by Russian researchers, primarily aimed at regulating cartilage and connective tissue. Its mechanism of action is thought to involve the modulation of cellular processes associated with aging and tissue regeneration. Specifically, Cartalax may influence the behavior of chondrocytes and fibroblasts, promoting their proliferation and differentiation, which is critical for maintaining healthy cartilage and connective tissue integrity.

Cytoprotection | Traumatic brain injury

Research peptide discovered via AI researcher. peptide-based therapeutic

Disrupts FOXO4-p53 | Senescent cell clearance

FOXO4-DRI (FOXO4-D-Retro-Inverso) is a synthetic peptide designed as a senolytic agent, targeting the interaction between FOXO4 and p53 to induce selective apoptosis in senescent cells. The mechanism of action involves disrupting the FOXO4-p53 complex, which is crucial for maintaining cellular senescence. By inhibiting this interaction, FOXO4-DRI promotes the death of senescent cells, potentially alleviating age-related pathologies and improving tissue function.

GH stimulation | Growth hormone deficiency

Tesamorelin + Ipamorelin GH Secretagogue Blend

Healing | High-Dose Three-Peptide Blend

High-Dose Three-Peptide Healing Blend

Stimulates GH release | Potential metabolic benefits

GH secretagogue blends are formulations designed to stimulate the secretion of growth hormone (GH) from the pituitary gland. These blends typically consist of various peptides and compounds that may enhance GH release, potentially influencing growth, metabolism, and overall health.

Bone formation | Osteoporosis treatment

Research peptide discovered via AI researcher. peptide analogue

GABA Modulation | Anxiolytic effects

NA Selank Amidate is a modified Selank analog with N-acetylation and C-terminal amidation designed to extend stability, studied for anxiolytic and nootropic effects.

Muscle Growth | Recovery Enhancement

Pegylated Mechano Growth Factor | IGF-1 Splice Variant

Modulation | Experimental research

Research peptide discovered via AI researcher. research peptide

Bioregulator | Testicular health

KEDG Tetrapeptide | Testicular Bioregulator

Immunomodulation | Immune system regulation

Research peptide discovered via AI researcher. research peptide

Copper delivery | Hair follicle support

AHK-Cu (Copper Tripeptide-3) is a synthetic alanine-histidine-lysine peptide bound to copper, studied topically for stimulating dermal papilla cells and supporting hair follicle health.

Cell Differentiation | Bronchial Epithelial Support

Bronchogen (AEDL) is a short synthetic tetrapeptide bioregulator studied in Russian research for supporting bronchial epithelial function and pulmonary tissue homeostasis.

Neuroprotection | Cognitive support

Cortagen (AEDP) is a synthetic tetrapeptide cortex bioregulator from the Khavinson family, researched primarily for neuroprotection, cognitive support, and recovery after brain or nerve injury.

Metabolic regulation | Obesity and type 2 diabetes

Research peptide discovered via AI researcher. peptide-based therapeutic

Dual agonist | Metabolic regulation

Research peptide discovered via AI researcher. peptide-based therapeutic

Skin rejuvenation | Photoaging support

Glow Protocol (GLOW) is a multi-peptide skin rejuvenation complex combining regenerative and pigment-modulating peptides studied for photoaging, dullness, and skin barrier support.

Healing | Tissue repair and inflammation modulation

The Glow Stack, comprising BPC-157, TB-500, and GHK-Cu, is a combination of peptides that has garnered interest for its potential roles in tissue repair, inflammation modulation, and skin health. Research into these peptides suggests various biological activities, though comprehensive clinical data on their combined effects is still limited.

Lipolytic | Fat-burning effects

HGH Fragment 176-191 is a synthetic C-terminal fragment of human growth hormone studied for its lipolytic (fat-burning) effects without the growth-promoting actions of full GH.

Metabolic regulation | Research peptide

Nisotirostide, also known as LY3457263, is a novel peptide that acts as a selective agonist for the neuropeptide Y2 (NPY2) receptor. This receptor is involved in various physiological processes, including appetite regulation and energy homeostasis. By activating the NPY2 receptor, nisotirostide is hypothesized to influence metabolic pathways that can lead to weight loss and improved glycemic control, making it a potential therapeutic option for conditions such as type 2 diabetes and obesity.