Peptides DB
Research-centric peptide and protocol reference hub

Triptorelin record · updated 9h ago

Metabolic & appetiteHealing & recoveryGrade A · human clinicalResearch use only
All 10 studiesJump to the evidenceCompare
What is Triptorelin used for?

Research peptide discovered via AI researcher. peptide analogue

How it works: GnRH agonist

Primarily researched for · Metabolic & appetiteRoute · Subcutaneous injection

Development stage

where Triptorelin sits between preclinical work and regulatory approval
  1. 1Current
    Preclinical
    Animal / in-vitro work
  2. 2Not reached
    Phase 1
    Safety in humans
  3. 3Not reached
    Phase 2
    Efficacy signal
  4. 4Not reached
    Phase 3
    Confirmatory trials
  5. 5Not reached
    Approved
    Cleared by a regulator

Stage is inferred from the highest trial phase in the indexed corpus and 84 registered trials. It describes the research record, not a recommendation.

Identity
NameTriptorelin
Chain length—
Molecular weight1,311.4 Da
FormulaC64H82N18O13
Structure typeNot established
ClassMetabolic
Research levelWell Studied
Discovered byThe Librarian · 2026

Mass and formula from PubChem CID 25074470. No verified residue count for this compound.

Pharmacology
MechanismGnRH agonist
RouteSubcutaneous injection
Half-life~3 hours
Time to peak1–2 hours
Durationvariable
Extraction confidence0.90
Effect profile · 0–5
These seven scores are generated by the Librarian — an autonomous agent running GPT-4o over the indexed studies, trials and label data for this compound. No human assigns them and no community vote moves them. Last recomputed Nov 3, 2026. How this works →
Research stats
Total studies10
Human / animal / cellular6 / 3 / 0
Highest trial phase—
Years covered2023–2026
Latest study2d ago
Publication history
20232026
Research funding
20 NIH projects · $1.4M awarded · through FY2018
Public grants naming this compound. Funding is interest, not evidence.
Safety signals
FAERS reports2,022
Serious AEs in animal work—
Community reports—
Positive —Neutral —Negative —
Records

Study register

10 rowsOpen in the library →
StudyTypeYearSummary depth
Comparative effectiveness of luteal phase support strategies in natural cycle frozen-thawed embryo transfer: a systematic review and network meta-analysis.
FindingNot reported in abstract.
review2026Full text read0.80
Proposed Method for Mass Spectrometric Measurement of the Gonadotropin-Releasing Hormone Agonist Deslorelin.
FindingDetectability optimized to <1 ppb.
Animal2026Full text read0.80
Comparison of cardiovascular events in patients with metastatic hormone sensitive prostate cancer treated with LHRH agonists to LHRH antagonists in the US: A retrospective cohort study.
FindingHR for MACE with LHRH-AG vs LHRH-AN was 0.86, 95% CI: 0.79-0.93.
Human2026Full text read0.80
Evaluation of triplet therapy combined with robot-assisted cytoreductive prostatectomy for high-volume metastatic prostate cancer: a multicentre randomised controlled trial protocol.
FindingNot reported in abstract.
Human2026Full text read0.70
Optimizing ovarian stimulation in oocyte donation: exploratory comparison of rhFSH (2:1) versus hp-hMG under PPOS protocols.
FindingMean number of good-morphology blastocysts per cycle was 4.5 with rhFSH:rhLH vs 2.0 with hp-hMG.
Human2023Full text read0.80
Treatment Outcomes in 84 Male Children with Accelerated Pubertal Progression: A Comparative Analysis ofGnRHa, Combined GH Therapy and Aromatase Inhibitor
FindingΔH/y of combination therapy was 8.49 ± 3.22 cm/y, GnRHa was 6.73 ± 1.95 cm/y, and AI was 7.75 ± 1.92 cm/y, P < 0.01.
Human2026Full text read0.80
Perceived Stress During Gender-Affirming Hormone Therapy: A Comparative Study of Feminizing and Masculinizing Hormone Therapy in an International Multicenter Prospective Cohort
FindingNo significant changes in perceived stress were observed after 3 months (-1.0, p = 0.21).
Human2025Full text read0.80
GnRH Agonist Triptorelin Induces Hepatic Fibrosis via Sex-Specific Oxidative and Inflammatory Responses in Adolescent Rats
FindingNot reported in abstract.
Animal2025Full text read0.70
Reproductive Axis Recovery Post Ovarian Stimulation and Gonadotropin Releasing Hormone Agonist (GnRH-a) Trigger, Observational Case Series
FindingOvulation was delayed to cycle day 21, compared to the predicted cycle day 14.
Human2025Full text read0.80
Pubertal Triptorelin Exposure Alters Hypothalamic Reproductive–Metabolic Integration in a Sex-Specific Manner
FindingNot reported in abstract.
Animal2026Full text read0.70

What people are saying

anecdotal · not evidence

Unverified first-hand accounts from public forums. These are not studies: nobody checked what was taken, whether it was what the label said, or what else was going on. They count for nothing in the evidence grade above and are shown because a reader searching Triptorelin will meet them anyway, and meeting them next to a graded evidence base is better than meeting them alone.

Community collection has not run yet, so this is an empty shelf rather than a quiet one — nothing has been read, and no conclusion about how much Triptorelin is discussed should be drawn from it.