Every peptide, graded by the evidence behind it.
HGH (somatropin) is recombinant human growth hormone, FDA-approved for pediatric and adult GH deficiency and several wasting and short-stature conditions; widely studied for body composition off-label.
Semaglutide is a synthetic analog of glucagon-like peptide-1 (GLP-1), a hormone involved in glucose metabolism and appetite regulation. As a GLP-1 receptor agonist, semaglutide enhances insulin secretion in response to elevated blood glucose levels, suppresses glucagon secretion, and slows gastric emptying, leading to improved glycemic control. Additionally, it promotes satiety, contributing to weight loss, which has made it a focus of research for managing both type 2 diabetes and obesity.
Glutathione (GSH) is a tripeptide composed of glutamine, cysteine, and glycine, recognized as the body's primary intracellular antioxidant. It plays a critical role in maintaining redox balance, detoxifying harmful compounds, and supporting immune function. GSH is also involved in various cellular processes, including the regulation of cell proliferation and apoptosis, making it essential for overall cellular health and function.
HCG (Human Chorionic Gonadotropin) is a glycoprotein hormone produced by the placenta during pregnancy, structurally similar to luteinizing hormone (LH). It plays a crucial role in regulating reproductive processes in both men and women. In clinical settings, HCG is primarily used to stimulate endogenous testosterone production in men with hypogonadism and to support fertility treatments in women, particularly in assisted reproductive technologies such as in vitro fertilization (IVF).
NAD+ (Nicotinamide adenine dinucleotide) is a crucial coenzyme involved in various metabolic processes, including energy production and cellular repair mechanisms. Recent research highlights its potential roles in protecting against oxidative stress and enhancing therapeutic efficacy in certain cancer treatments.
Oxytocin is a neuropeptide synthesized in the hypothalamus and released by the posterior pituitary gland. It plays a significant role in various physiological and behavioral processes, including social bonding, reproductive behaviors, emotional regulation, childbirth, and lactation. The mechanisms of action of oxytocin involve its binding to specific receptors in the brain and peripheral tissues, influencing neural circuits associated with social cognition, attachment, and stress response.
Evidence map
How much evidence exists, and how strong it is — the gap is the storyOpen the full map →still preclinical
HGH (somatropin) is recombinant human growth hormone, FDA-approved for pediatric and adult GH deficiency and several wasting and short-stature conditions; widely studied for body composition off-label.