Peptides DB

Research-centric peptide and protocol reference hub

Semaglutide

Research-centric overview

Peptide1 protocol

Summary pending admin curation in the CMS.

Community effect votes, structured logs, and side-effect summaries.

Effect profile (overview)

Aggregate AI baseline blended with community voting. Hover to inspect effect strengths per category.

Effect profile (AI + community): Metabolic & appetite 5.0/5 · Skin & aesthetics 3.0/5Healing 0.0Muscle 0.0Metabolic 5.0Neuro 0.0Sleep 0.0Inflammation 0.0Skin 3.0

Effect scores blend an AI baseline with community votes. Open the full chart to see sliders and vote on each category.

Research log summary heatmap

Compact view of how logs describe shifts in pain, sleep, and performance (−5 to +5). Treat this as qualitative, anonymous signal only.

Pain / discomfort0/5
Sleep / recovery+1/5
Performance / output+1/5

Based on 1 anonymized research log. Scroll down for full context and methodology.

Anonymous side-effect patterns

Rough heatmap of anonymous side-effect and positive-signal tags — a "most-mentioned" snapshot, not safety or efficacy advice.

46%reduced appetite
35%early satiety
19%nausea

Research feed

Approved research items linked to this peptide.

Semantic Scholar search for SemaglutideSemanticScholar
Tirzepatide vs. Semaglutide: clinical decision-making in the GLP-1 landscape.PubMed

Expert opinion on pharmacotherapy · 2025

Sustained weight reduction with once-weekly semaglutide: results from a real-world retrospective cohort study in the United States (SCOPE 24 months).PubMed

Current medical research and opinion · 2025

GLP-1 receptor agonist utilization is associated with a low risk of Anesthesia-related complications prior to total joint arthroplasty.PubMed

European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2025

External databases

Helpful external resources for additional structural, pharmacologic, and literature context. These are third-party databases; always cross-check details with primary research.

Community notes

No public comments yet. Use the form below to submit research questions or observations for admin review.

Submitted comments are queued for admin moderation.

Community research logs (detail)

Showing the latest 1 logs out of 1.

Goal: weight / appetite

Context: sedentary / light 46-55

Duration ~16.0 weeks • ~1.0 doses/week

Δ scores
Pain +0Sleep +1Perf +1

Weekly GLP-1 agonist with gradual uptitration alongside nutrition coaching. Tracking appetite, weight trend, GI side-effects, and energy levels.

How to read these logs

Each entry is a single, anonymized “n=1” summary with relative change sliders from −5 to +5. Higher positive values indicate perceived improvement; negative values indicate perceived worsening.

Context (training level, age band, duration, and dosing frequency) is shown so you can quickly skim for patterns or outliers. Treat this as qualitative signal layered on top of study data, not as a substitute for controlled trials.

Anonymous side-effect reporting (detail)

This section describes how anonymous side-effect reports are aggregated into the heatmap above. Reports are anonymous and unverified, and should be read alongside primary safety data.

Use the "Report side effects" button to open a focused popup form. Please keep descriptions neutral and avoid medical language; think in terms of "nausea", "flushing", "vivid dreams", etc.

Quick tone breakdown of submitted side-effect tags:

PositiveNegativeNeutral / mixed

Top reported tags so far (color reflects tone):

46%reduced appetite
35%early satiety
19%nausea

Questions & answers

Ask focused, research-style questions; answers can link to studies or protocols.

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