Peptides DB
Research-centric peptide and protocol reference hub
Skin & aesthetics

Best peptides for Sexual Health

PT-141 (Bremelanotide), Kisspeptin, HCG, Gonadorelin, HMG, Oxytocin, Melanotan II, and Prostamax are the most-studied peptides for sexual function, libido, fertility, and reproductive hormone modulation. Each entry below links to its full research profile.

5
peptides matched
Ranked by approved-study count
Gonadorelin (GnRH): Healing 2.0, Muscle 0.0, Metabolic 0.0, Neuro 1.0, Sleep 0.0, Immune 0.0, Skin 0.0Healing & recovery — 2.0 / 5Neuro & mood — 1.0 / 5
Gonadorelin (GnRH)Extensively Studied

Gonadotropin-Releasing Hormone | GnRH Agonist

Gonadorelin is synthetic GnRH, a decapeptide that stimulates pituitary release of LH and FSH in pulsatile fashion — used diagnostically and to support the reproductive hormone axis.

18 studiesDominant effect: healingFull profile →
HMG (Human Menopausal Gonadotropin): Healing 2.0, Muscle 0.0, Metabolic 0.0, Neuro 0.0, Sleep 0.0, Immune 0.0, Skin 0.0Healing & recovery — 2.0 / 5

Human Menopausal Gonadotropin | FSH/LH Fertility Hormone

HMG (Human Menopausal Gonadotropin) is a urine-derived injectable containing FSH and LH activity, used clinically to drive ovulation in IVF cycles and restore spermatogenesis in hypogonadotropic men.

17 studiesDominant effect: healingFull profile →
HCG (Human Chorionic Gonadotropin): Healing 3.0, Muscle 2.0, Metabolic 3.0, Neuro 1.0, Sleep 0.0, Immune 1.0, Skin 2.0Healing & recovery — 3.0 / 5Muscle & body comp — 2.0 / 5Metabolic & appetite — 3.0 / 5Neuro & mood — 1.0 / 5Inflammation & immune — 1.0 / 5Skin & aesthetics — 2.0 / 5

Human Chorionic Gonadotropin | LH Receptor Agonist

HCG (Human Chorionic Gonadotropin) is an FDA-approved glycoprotein hormone that mimics luteinizing hormone, used to stimulate endogenous testosterone production and support fertility in men and women.

16 studiesDominant effect: healingFull profile →
Melanotan II: Healing 0.0, Muscle 0.0, Metabolic 0.0, Neuro 2.0, Sleep 0.0, Immune 0.0, Skin 5.0Neuro & mood — 2.0 / 5Skin & aesthetics — 5.0 / 5
Melanotan IIWell Studied

Synthetic Melanocortin Peptide | Tanning & Sexual Function

### Summary Melanotan II is a synthetic analog of the naturally occurring peptide hormone alpha-melanocyte-stimulating hormone (α-MSH), primarily studied for its effects on skin pigmentation and potential therapeutic applications. Research has also explored its impact on mood and stress responses, though caution is advised due to potential side effects and safety concerns.

9 studiesDominant effect: aestheticFull profile →
Kisspeptin (KP-10): Healing 0.0, Muscle 0.0, Metabolic 1.0, Neuro 4.0, Sleep 0.0, Immune 0.0, Skin 0.0Metabolic & appetite — 1.0 / 5Neuro & mood — 4.0 / 5

KISS1 Gene Product | Reproductive Neuropeptide

Kisspeptin (KP-10) is a 10-amino acid KISS1 gene fragment that activates KISS1R to drive GnRH release, studied as an upstream regulator of reproductive hormones and fertility.

5 studiesDominant effect: neuroFull profile →

Related reading

Best-Of Roundups
Best Peptides for Libido: Evidence-Backed Options

PT-141, Melanotan II, Kisspeptin, Oxytocin — the peptides with usable libido evidence. PT-141 is FDA-approved for HSDD; the others are mechanism-relevant but less clinically validated.

4 min read
Guides
Peptide Therapy: What It Is, Who It's For, How It Works

Peptide therapy delivers research peptides under clinician supervision for weight loss, recovery, hormonal optimization, and other indications. Here's the evidence, the landscape, and how to evaluate a provider.

6 min read

Dosing for approved agents comes from the label, not from this site. If you are working out injection volumes, the reconstitution calculator converts mg per vial into syringe units, and how to use peptides covers storage and handling. Neither is a recommendation to use anything.

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Medical disclaimer

Rankings reflect how much indexed research exists, not how safe or effective anything is for you. Nothing here is medical advice. Most peptides on this site are not approved drugs.