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Wolverine Stack (BPC-157/TB-500) record · updated 10h ago

Healing & recoveryInflammation & immuneGrade D · emergingResearch use only
Evidence for its componentsCompare
What is Wolverine Stack (BPC-157/TB-500) used for?

BPC-157 + TB-500 | Tissue Repair & Recovery Protocol

How it works: Body-protective compound (pentadecapeptide); cytoprotective, pro-angiogenic signaling

Primarily researched for · Healing & recoveryRoute · Subcutaneous / oral (research use)

Development stage

where Wolverine Stack (BPC-157/TB-500) sits between preclinical work and regulatory approval
  1. 1Current
    Preclinical
    Animal / in-vitro work
  2. 2Not reached
    Phase 1
    Safety in humans
  3. 3Not reached
    Phase 2
    Efficacy signal
  4. 4Not reached
    Phase 3
    Confirmatory trials
  5. 5Not reached
    Approved
    Cleared by a regulator

Stage is inferred from the highest trial phase in the indexed corpus. It describes the research record, not a recommendation.

Identity
NameWolverine Stack (BPC-157/TB-500)
Chain length—
Molecular weight—
Formula—
Structure type—
ClassHealing
Research levelWell Studied
Discovered byCurated master list · 2026
Pharmacology
MechanismBody-protective compound (pentadecapeptide); cytoprotective, pro-angiogenic signaling
RouteSubcutaneous / oral (research use)
Half-life—
Time to peak—
Duration—
Extraction confidence0.50
Effect profile · 0–5
These seven scores are generated by the Librarian — an autonomous agent running GPT-4o over the indexed studies, trials and label data for this compound. No human assigns them and no community vote moves them. Last recomputed Jul 16, 2026. How this works →
Research stats
Total studies0
Human / animal / cellular0 / 0 / 0
Highest trial phase—
Years covered—
Latest study—
Publication history
No publication years on file
——
Research funding
—no NIH grants found
Safety signals
FAERS reportsnone recorded
Serious AEs in animal work—
Community reports—
Positive —Neutral —Negative —
Records

Study register

no studies of its own · newest 12 of 25 from its componentsOpen in the library →
No direct evidence

No study in this library has tested this combination directly. The papers below examined its components individually — each row is labelled with the single compound that study looked at.

Evidence for one component is not evidence for the combination. Nothing below measured what happens when these compounds are used together.

ComponentsBPC-157TB-500
StudyTypeYearSummary depth
Investigational Peptides in Orthopaedic Practice: Evidence, Safety, and Patient Counseling for BPC-157, Thymosin Beta-4, and TB-500.
FindingNot reported in abstract.
review2023Full text read0.80
Investigational Peptides in Orthopaedic Practice: Evidence, Safety, and Patient Counseling for BPC-157, Thymosin Beta-4, and TB-500.
TakeawayOrthopaedic clinicians should be cautious about recommending TB-500 due to the lack of validated human efficacy and safety data.
review2026Full text read0.80
Human evidence for BPC-157 in orthopaedic and regenerative medicine: a systematic review of efficacy and safety.
FindingNot reported in abstract.
review2023Full text read0.80
BPC 157 in Rodent Ischemia-Reperfusion Injury: A Critical Review of Preclinical Evidence.
FindingNot reported in abstract.
review2020Full text read0.70
De novo cardiomyocytes from within the activated adult heart after injury.
TakeawayNot reported in abstract.
—2011Title only0.10
In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes.
TakeawayNot reported in abstract.
Animal2012Title only0.10
JMB2403, a potential best-in-class PD-1-dependent IL2Rβγ-activating tri-specific antibody for safe and potent immunotherapy.
FindingNot reported in abstract.
Animal2026Full text read0.70
First Case Report of Triple Recurrent Cholangitis of "Coildocholithiasis," Following Hepatic Artery Pseudoaneurysm Embolization.
FindingNot reported in abstract.
Human2023Full text read0.80
OTUD5 promotes AML progression by stabilizing SLC7A11 to suppress ferroptosis.
FindingNot reported in abstract.
Human2026Full text read0.70
Construction and validation of a prediction model for graft failure in pediatric liver transplant recipients based on the APRI-ALBI score: a retrospective study of 289 cases.
FindingAUC of 0.706 for the nomogram predicting graft failure.
Human2026Full text read0.80
Mechanism of Fibrotic Anastomosis Formation in Endoscopic Ultrasound-guided Hepaticogastrostomy Using a Plastic Stent: Insights From an Autopsy Case of Perihilar Cholangiocarcinoma.
FindingNot reported in abstract.
Human2023Full text read0.70
Endoscopic Diagnosis of Necator americanus Infection Presenting With Persistent Iron-Deficiency Anemia: Usefulness of Image-Enhanced Endoscopy and Capsule Endoscopy.
FindingNot reported in abstract.
Human2023Full text read0.80

What people are saying

anecdotal · not evidence

Unverified first-hand accounts from public forums. These are not studies: nobody checked what was taken, whether it was what the label said, or what else was going on. They count for nothing in the evidence grade above and are shown because a reader searching Wolverine Stack (BPC-157/TB-500) will meet them anyway, and meeting them next to a graded evidence base is better than meeting them alone.

Community collection has not run yet, so this is an empty shelf rather than a quiet one — nothing has been read, and no conclusion about how much Wolverine Stack (BPC-157/TB-500) is discussed should be drawn from it.