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GHK-Cu record · updated 10h ago

Healing & recoverySkin & aestheticsGrade C · preclinicalResearch use only
All 22 studiesJump to the evidenceCompare
What is GHK-Cu used for?

Copper-binding tripeptide widely used in skin, hair, and wound-healing contexts, with systemic effects explored in research.

How it works: Copper-binding tripeptide (GHK-Cu); tissue-remodeling / regenerative signaling

Primarily researched for · Healing & recoveryRoute · Topical / subcutaneous

Development stage

where GHK-Cu sits between preclinical work and regulatory approval
  1. 1Current
    Preclinical
    Animal / in-vitro work
  2. 2Not reached
    Phase 1
    Safety in humans
  3. 3Not reached
    Phase 2
    Efficacy signal
  4. 4Not reached
    Phase 3
    Confirmatory trials
  5. 5Not reached
    Approved
    Cleared by a regulator

Stage is inferred from the highest trial phase in the indexed corpus and 67 registered trials. It describes the research record, not a recommendation.

Identity
NameGHK-Cu
Chain length—
Molecular weight400.9 Da
FormulaC14H21CuN6O4-
Structure typeSmall molecule
ClassHealing
Research levelPreclinical
Discovered byAdded before provenance tracking · 2025

Mass and formula from PubChem CID 139035031. No verified residue count for this compound.

Pharmacology
MechanismCopper-binding tripeptide (GHK-Cu); tissue-remodeling / regenerative signaling
RouteTopical / subcutaneous
Half-life—
Time to peak—
Duration—
Extraction confidence0.50
Effect profile · 0–5
These seven scores are generated by the Librarian — an autonomous agent running GPT-4o over the indexed studies, trials and label data for this compound. No human assigns them and no community vote moves them. Last recomputed Aug 31, 2026. How this works →
Research stats
Total studies22
Human / animal / cellular0 / 9 / 6
Highest trial phasePreclinical
Years covered2025–2026
Latest study17h ago
Publication history
20252026
Research funding
8,740 NIH projects · $23.3M awarded · through FY2026
Public grants naming this compound. Funding is interest, not evidence.
Safety signals
FAERS reports12
Serious AEs in animal work—
Community reports—
Positive —Neutral —Negative —
Records

Study register

22 rows · newest 12 shownOpen in the library →
StudyTypeYearSummary depth
A brain-targeted biomimetic iron-porphyrin covalent organic framework nanoplatform for Alzheimer's disease: synergistic intervention via antioxidant, Aβ-regulating and immunomodulatory effects.
FindingCopper-ion chelation rate of 41.78%.
In vitro2026Full text read0.70
Systemic Copper Chelation Reduces Collagen Deposition and Preserves Secretory Function in Irradiated Mouse Salivary Glands.
FindingNot reported in abstract.
Animal2026Full text read0.80
Asymmetric-interfacial nanofibrous membranes with diode-like exudate transport for nanozyme-catalyzed antibacterial wound healing.
Finding99.8% wound closure by day 12.
Animal2026Full text read0.80
Superconducting 2D cuprate with a single CuO(2) plane.
FindingApproximately 10% reduction in optimal superconducting transition temperature.
—2026Partial text0.50
Ultralong sheathed single-metal-atom chains synthesized under high pressure.
TakeawayNot reported in abstract.
—2026Title only0.10
Ultrasensitive low-density lipoprotein monitoring in early cardiovascular risk assessment via Cu-MOF-Apt/MoS₂ fluorescent nanosensor.
Findingultra-low detection limit (0.0789 ng/mL)
In vitro2026Full text read0.70
pH and temperature-dependent structural and functional stability of hemocyanin from Tachypleus gigas: A multispectroscopic, phenoloxidase activity and computational study.
Finding80% phenoloxidase activity up to 70 °C.
In vitro2026Full text read0.70
Room-temperature multiferroicity in all-van der Waals heterostructures.
TakeawayNot reported in abstract.
—2026Title only0.10
Mining triggers extensive additional deforestation in sub-Saharan Africa.
TakeawayNot reported in abstract.
—2026Title only0.10
Orbital magnetoresistance in the antiferromagnet CoO driven by dynamic orbital angular momentum.
TakeawayNot reported in abstract.
—2026Title only0.10
Surface-dominant transport in Weyl semimetal NbAs nanowires for next-generation interconnects.
TakeawayNot reported in abstract.
—2026Title only0.10
Partial substitution of organic trace minerals in sow diets over multiple parities and the impact on claw health, productivity, and longevity.
FindingLactation weight loss decreased with treatment (P = 0.02).
Animal2026Full text read0.80

What people are saying

anecdotal · not evidence

Unverified first-hand accounts from public forums. These are not studies: nobody checked what was taken, whether it was what the label said, or what else was going on. They count for nothing in the evidence grade above and are shown because a reader searching GHK-Cu will meet them anyway, and meeting them next to a graded evidence base is better than meeting them alone.

Community collection has not run yet, so this is an empty shelf rather than a quiet one — nothing has been read, and no conclusion about how much GHK-Cu is discussed should be drawn from it.

Articles mentioning GHK-Cu