Peptides DB

Research-centric peptide and protocol reference hub

GHK-Cu

Research-centric overview

Peptide3 protocols

Copper-binding tripeptide widely used in skin, hair, and wound-healing contexts, with systemic effects explored in research.

Community effect votes, structured logs, and side-effect summaries.

Effect profile (overview)

Aggregate AI baseline blended with community voting. Hover to inspect effect strengths per category.

Effect profile (AI + community): Healing & recovery 4.0/5 · Inflammation & immune 3.0/5 · Skin & aesthetics 5.0/5Healing 4.0Muscle 0.0Metabolic 0.0Neuro 0.0Sleep 0.0Inflammation 3.0Skin 5.0

Effect scores blend an AI baseline with community votes. Open the full chart to see sliders and vote on each category.

Research log summary heatmap

Compact view of how logs describe shifts in pain, sleep, and performance (−5 to +5). Treat this as qualitative, anonymous signal only.

Pain / discomfort0/5
Sleep / recovery0/5
Performance / output+2/5

Based on 10 anonymized research logs. Scroll down for full context and methodology.

Anonymous side-effect patterns

Rough heatmap of anonymous side-effect and positive-signal tags — a "most-mentioned" snapshot, not safety or efficacy advice.

58%improved skin texture
16%localized irritation
13%transient tingling
3%gi upset
3%headache

Research feed

Approved research items linked to this peptide.

Sort:Newest·Upvoted
Semantic Scholar search for GHK-CuSemanticScholar
View source
Copper Complexes with New Glycyl-l-histidyl-l-lysine-Hyaluronan Conjugates Show Antioxidant Properties and Osteogenic and Angiogenic Synergistic Effects.PubMed

Bioconjugate chemistry · 2025

View source
Exploring the beneficial effects of GHK-Cu on an experimental model of colitis and the underlying mechanisms.PubMed

Frontiers in pharmacology · 2025

View source
An injectable hydroxyapatite microsphere filler loaded with GHK-Cu tripeptide for anti-Inflammatory and antioxidant.PubMed

Colloids and surfaces. B, Biointerfaces · 2025

View source

External databases

Helpful external resources for additional structural, pharmacologic, and literature context. These are third-party databases; always cross-check details with primary research.

PubChem search: GHK-CuPubMed searchGoogle Scholar searchSemantic Scholar search

Protocols

View all protocols
Tissue repair micro-cycle (BPC-157 + TB-500 + GHK-Cu)

Exploratory tissue repair protocol stacking BPC-157, TB-500, and GHK-Cu for soft-tissue and connective-tissue support.

Glow Stack

Klow Stack

Community notes

No public comments yet. Use the form below to submit research questions or observations for admin review.

Submitted comments are queued for admin moderation.

Community research logs (detail)

Showing the latest 5 logs out of 10.

Goal: injury / tissue repair

Context: recreational • 26-35

Duration ~6.0 weeks

Δ scores
Pain +1Sleep +0Perf +1

GHK-Cu used on scar tissue around an old surgical site alongside massage and basic rehab work. Subjective improvement in scar pliability and local tightness.

Goal: skin / cosmetic

Context: sedentary / light • 36-45

Duration ~8.0 weeks

Δ scores
Pain +0Sleep +1Perf +0

Topical GHK-Cu cream to face and neck most evenings. Tracking skin texture, fine lines, and general 'glow' with photos; also paying attention to irritation or breakouts.

Goal: joint / tendon comfort

Context: unspecified training level • age not given

Duration not specified

Δ scores
Pain -4Sleep -3Perf +5

Goal: injury / tissue repair

Context: unspecified training level • age not given

Duration not specified

Δ scores
Pain +1Sleep +0Perf +0

Goal: injury / tissue repair

Context: unspecified training level • age not given

Duration not specified

Δ scores
Pain +0Sleep +0Perf +3

How to read these logs

Each entry is a single, anonymized “n=1” summary with relative change sliders from −5 to +5. Higher positive values indicate perceived improvement; negative values indicate perceived worsening.

Context (training level, age band, duration, and dosing frequency) is shown so you can quickly skim for patterns or outliers. Treat this as qualitative signal layered on top of study data, not as a substitute for controlled trials.

Anonymous side-effect reporting (detail)

This section describes how anonymous side-effect reports are aggregated into the heatmap above. Reports are anonymous and unverified, and should be read alongside primary safety data.

Use the "Report side effects" button to open a focused popup form. Please keep descriptions neutral and avoid medical language; think in terms of "nausea", "flushing", "vivid dreams", etc.

Quick tone breakdown of submitted side-effect tags:

PositiveNegativeNeutral / mixed

Top reported tags so far (color reflects tone):

58%improved skin texture
16%localized irritation
13%transient tingling

Questions & answers

Ask focused, research-style questions; answers can link to studies or protocols.

No questions yet. You can ask something focused about mechanisms, study design, or protocol choices below.