Refreshed content for GHK-Cuai_activityai-researcherApr 16, 2026
Pulled 4 linked studies for context. - **content** updated: Body content rewritten (+280 chars; was 921, now 1201).
No external link
Copper-binding tripeptide widely used in skin, hair, and wound-healing contexts, with systemic effects explored in research.
Community effect votes, structured logs, and side-effect summaries.
Effect profile (overview)
Aggregate AI baseline blended with community voting. Hover to inspect effect strengths per category.
Effect scores blend an AI baseline with community votes. Open the full chart to see sliders and vote on each category.
Research log summary heatmap
Compact view of how logs describe shifts in pain, sleep, and performance (−5 to +5). Treat this as qualitative, anonymous signal only.
Pain / discomfort0/5
Sleep / recovery0/5
Performance / output+2/5
Based on 10 anonymized research logs. Scroll down for full context and methodology.
Anonymous side-effect patterns
Rough heatmap of anonymous side-effect and positive-signal tags — a "most-mentioned" snapshot, not safety or efficacy advice.
58%improved skin texture
positive / signal16%localized irritation
negative / caution13%transient tingling
mixed / neutral3%gi upset
negative / caution3%headache
negative / cautionResearch footprint
Last analyzed Apr 17, 20267
Studies indexed
0
Human
1
Animal
6
AI analyzed
Evidence mix0% human · 14% animal · 0% cellular · 0% review
Highest phase: PreclinicalYears covered: 2026
Librarian pulse — latest actionsFull changelog ↓
- Apr 16, 5:13 PMRefreshedRefreshed content for GHK-Cu
Research & intelligence feed
Studies, clinical trials, community discussions, and news.
A Phase 2, Randomized, Double-Blind, Vehicle-Controlled, Split-Wound Study of Topical GHK-Cu (Copper(II)-Peptide Complex) Gel to Accelerate Re-Epithelialization of Standardized Acute Skin Wounds in Healthy AdultsClinical TrialClinicalTrials.govApr 16, 2026
This study evaluated the effects of topical GHK-Cu gel on re-epithelialization of standardized acute skin wounds in healthy adults. The study was designed as a Phase 2, randomized, double-blind, vehicle-controlled trial. Not reported in abstract.
Phase: PHASE2Status: RECRUITING
A Phase IV Open-label Trial Assessing the Impact on Skin Quality, Hydration, and Barrier of Three (3) Hydrafacial Treatments in Adults of Fitzpatrick Skin Types I-VIClinical TrialClinicalTrials.govApr 16, 2026
This study assessed the impact of three Hydrafacial treatments on skin quality, hydration, and barrier function in adults of Fitzpatrick Skin Types I-VI. The trial was open-label and classified as Phase IV. No therapeutic claims were made.
Phase: PHASE4Status: COMPLETED
Semantic Scholar search for GHK-CuStudySemanticScholarDec 12, 2025
Copper Complexes with New Glycyl-l-histidyl-l-lysine-Hyaluronan Conjugates Show Antioxidant Properties and Osteogenic and Angiogenic Synergistic Effects.StudyPubMedDec 12, 2025
Not reported in abstract.
Exploring the beneficial effects of GHK-Cu on an experimental model of colitis and the underlying mechanisms.StudyPubMedDec 12, 2025
Not reported in abstract.
An injectable hydroxyapatite microsphere filler loaded with GHK-Cu tripeptide for anti-Inflammatory and antioxidant.StudyPubMedDec 12, 2025
Not reported in abstract.
Popular stacks
Most commonly stacked peptides based on community research logs.
External databases
Helpful external resources for additional structural, pharmacologic, and literature context. These are third-party databases; always cross-check details with primary research.
Community notes
No comments yet. Share research notes, citations, or observations below.
Community research logs (detail)
Showing the latest 5 logs out of 10.
Goal: injury / tissue repair
Context: recreational • 26-35
Duration ~6.0 weeks
Δ scores
Pain +1Sleep +0Perf +1
GHK-Cu used on scar tissue around an old surgical site alongside massage and basic rehab work. Subjective improvement in scar pliability and local tightness.
Goal: skin / cosmetic
Context: sedentary / light • 36-45
Duration ~8.0 weeks
Δ scores
Pain +0Sleep +1Perf +0
Topical GHK-Cu cream to face and neck most evenings. Tracking skin texture, fine lines, and general 'glow' with photos; also paying attention to irritation or breakouts.
Goal: joint / tendon comfort
Context: unspecified training level • age not given
Duration not specified
Δ scores
Pain -4Sleep -3Perf +5
Goal: injury / tissue repair
Context: unspecified training level • age not given
Duration not specified
Δ scores
Pain +1Sleep +0Perf +0
Goal: injury / tissue repair
Context: unspecified training level • age not given
Duration not specified
Δ scores
Pain +0Sleep +0Perf +3
How to read these logs
Each entry is a single, anonymized “n=1” summary with relative change sliders from −5 to +5. Higher positive values indicate perceived improvement; negative values indicate perceived worsening.
Context (training level, age band, duration, and dosing frequency) is shown so you can quickly skim for patterns or outliers. Treat this as qualitative signal layered on top of study data, not as a substitute for controlled trials.
Anonymous side-effect reporting (detail)
This section describes how anonymous side-effect reports are aggregated into the heatmap above. Reports are anonymous and unverified, and should be read alongside primary safety data.
Use the "Report side effects" button to open a focused popup form. Please keep descriptions neutral and avoid medical language; think in terms of "nausea", "flushing", "vivid dreams", etc.
Quick tone breakdown of submitted side-effect tags:
PositiveNegativeNeutral / mixed
Top reported tags so far (color reflects tone):
58%improved skin texture
positive / signal16%localized irritation
negative / caution13%transient tingling
mixed / neutralLibrarian Changelog
Every time the Librarian touches this peptide — discovering, refreshing, scoring, or verifying — it logs the action here.
1d agoRefreshai-researcher85%
Refreshed content for GHK-Cu