Peptides DB
Research-centric peptide and protocol reference hub

DSIP record · updated 18h ago

Sleep & circadianNeuro & moodGrade B · human evidenceResearch use only
All 20 studiesJump to the evidenceCompare
What is DSIP used for?

Delta Sleep-Inducing Peptide, primarily discussed for sleep quality, stress modulation, and pain.

How it works: Influences sleep regulation, stress modulation, and pain relief

Primarily researched for · Sleep & circadian

Development stage

where DSIP sits between preclinical work and regulatory approval
  1. 1Current
    Preclinical
    Animal / in-vitro work
  2. 2Not reached
    Phase 1
    Safety in humans
  3. 3Not reached
    Phase 2
    Efficacy signal
  4. 4Not reached
    Phase 3
    Confirmatory trials
  5. 5Not reached
    Approved
    Cleared by a regulator

Stage is inferred from the highest trial phase in the indexed corpus and 42 registered trials. It describes the research record, not a recommendation.

Identity
NameDSIP
Chain length9 amino acids
SequenceWAGGDASGE
Molecular weight848.8 Da
FormulaC35H48N10O15
Structure typePeptide
ClassSleep
Research levelPreclinical
Discovered byAdded before provenance tracking · 2025

Mass and formula from PubChem CID 68816. The chain length is only shown where the residues account for that mass, so a figure here has been checked against it rather than taken on trust.

Pharmacology
MechanismInfluences sleep regulation, stress modulation, and pain relief
Route—
Half-life—
Time to peak—
Duration—
Extraction confidence0.70
Effect profile · 0–5
These seven scores are generated by the Librarian — an autonomous agent running GPT-4o over the indexed studies, trials and label data for this compound. No human assigns them and no community vote moves them. Last recomputed Aug 27, 2026. How this works →
Research stats
Total studies20
Human / animal / cellular7 / 5 / 4
Highest trial phasePreclinical
Years covered2010–2026
Latest study5d ago
Publication history
20102026
Research funding
13 NIH projects · $564k awarded · through FY2017
Public grants naming this compound. Funding is interest, not evidence.
Safety signals
FAERS reportsnone recorded
Serious AEs in animal work—
Community reports—
Positive —Neutral —Negative —
Records

Study register

20 rows · newest 12 shownOpen in the library →
StudyTypeYearSummary depth
Biosensing technologies for cannabinoid monitoring in pain management: Current methods, clinical needs, and translational challenges.
TakeawayPortable electrochemical sensors and compact optical platforms may soon be useful for cannabinoid monitoring, but many technologies still need validation in real patient samples.
review2026Full text read0.80
EFS-NET: EEG-fNIRS multi-scale fusion network based on spatial calibration.
Finding81.69 ± 9.49% classification accuracy on Mental Arithmetic dataset.
review2023Full text read0.70
Noninvasive assessment of Doppler-derived estimated fetal interatrial pressure-gradient indices using ductus venosus and pulmonary vein velocities in late-onset fetal growth restriction: a prospective case-control study.
FindingPulmonary vein D-wave velocity was significantly reduced in FGR fetuses (18.20 [IQR 13.43-22.40] vs. 20.90 [IQR 15.97-25.60] cm/s; p=0.021).
Human2026Full text read0.80
Ginkgo biloba extract 50 alleviates memory and synaptic plasticity deficits by inhibiting neuroinflammation via the blockage of ATP-P2X7R axis in presenilin 1/2 conditional double knockout mice.
FindingNot reported in abstract.
Animal2026Full text read0.80
Diverse binding poses of agonistic neurotoxins on human Na(v)1.6.
FindingNot reported in abstract.
In vitro2026Title only0.20
Minimally processed, human-grade diet alters canine epigenetic ageing: Results from a pilot study.
FindingDelta age decreased from 2.75 to 1.80 years in the MPHGF group over 6 months, p=0.02.
Animal2023Full text read0.80
An adaptor for feedback regulation of heme biosynthesis by a mitochondrial protease.
TakeawayNot reported in abstract.
In vitro2026Title only0.10
Developing the NOMI framework for food and nutrition security in a climate-exposed delta: qualitative evidence from the Indian Sundarbans.
FindingNot reported in abstract.
Human2026Full text read0.70
Bu-Sui-Dan promotes angiogenesis to mitigate age-related osteoporosis via the ZEB1/Notch1 axis.
FindingBSD significantly improved bone mineral density, p<0.001.
Animal2026Full text read0.70
Olfactory Perception and Neural Rhythms: A Simulation-Based EEG Analysis Using Power Spectral Density FeaturesOlfactory perception and neural rhythms: a simulation-based eeg analysis using power spectral density features.
Finding99.67% classification accuracy for distinguishing olfactory conditions.
In vitro2026Full text read0.70
A qEEG-based prognostic model for cognitive impairment after ischemic stroke: Development and internal validation.
FindingHigher occipital DAR associated with increased risk (OR 2.09, 95% CI 1.45-3.39).
Human2026Full text read0.80
Early hemodynamic assessment and longitudinal imaging for predicting graft outcomes post-transplant.
FindingHepatic artery RI < 0.55 within 4 days post-transplant linked to EAD, negative predictive value 92.2%.
Human2026Full text read0.80

What people are saying

anecdotal · not evidence

Unverified first-hand accounts from public forums. These are not studies: nobody checked what was taken, whether it was what the label said, or what else was going on. They count for nothing in the evidence grade above and are shown because a reader searching DSIP will meet them anyway, and meeting them next to a graded evidence base is better than meeting them alone.

Community collection has not run yet, so this is an empty shelf rather than a quiet one — nothing has been read, and no conclusion about how much DSIP is discussed should be drawn from it.

Articles mentioning DSIP