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NA Semax Amidate (N-Acetyl Semax Amidate) record · updated 18h ago

Neuro & moodHealing & recoveryGrade B · human evidenceResearch use only
All 5 studiesJump to the evidenceCompare
What is NA Semax Amidate (N-Acetyl Semax Amidate) used for?

NA Semax Amidate is a modified heptapeptide analog of Semax (ACTH 4-10 fragment) studied for cognitive enhancement, neuroprotection, and BDNF/NGF modulation in preclinical research.

How it works: ACTH(4–10) analog; neuroprotective / nootropic

Primarily researched for · Neuro & moodRoute · Intranasal (research use)

Development stage

where NA Semax Amidate (N-Acetyl Semax Amidate) sits between preclinical work and regulatory approval
  1. 1Current
    Preclinical
    Animal / in-vitro work
  2. 2Not reached
    Phase 1
    Safety in humans
  3. 3Not reached
    Phase 2
    Efficacy signal
  4. 4Not reached
    Phase 3
    Confirmatory trials
  5. 5Not reached
    Approved
    Cleared by a regulator

Stage is inferred from the highest trial phase in the indexed corpus. It describes the research record, not a recommendation.

Identity
NameNA Semax Amidate (N-Acetyl Semax Amidate)
Chain length7 amino acids
Molecular weight855 Da
FormulaC39H54N10O10S
Structure typePeptide
ClassCognitive
Research levelPreclinical
Discovered byCurated master list · 2026

Mass and formula from PubChem CID 172638603. The chain length is only shown where the residues account for that mass, so a figure here has been checked against it rather than taken on trust.

Pharmacology
MechanismACTH(4–10) analog; neuroprotective / nootropic
RouteIntranasal (research use)
Half-life—
Time to peak—
Duration—
Extraction confidence0.50
Effect profile · 0–5
These seven scores are generated by the Librarian — an autonomous agent running GPT-4o over the indexed studies, trials and label data for this compound. No human assigns them and no community vote moves them. Last recomputed Oct 3, 2026. How this works →
Research stats
Total studies5
Human / animal / cellular4 / 1 / 0
Highest trial phase—
Years covered2026
Latest study15d ago
Publication history
20262026
Research funding
—no NIH grants found
Safety signals
FAERS reportsnone recorded
Serious AEs in animal work—
Community reports—
Positive —Neutral —Negative —
Records

Study register

5 rowsOpen in the library →
StudyTypeYearSummary depth
Increasing Direct-to-Consumer Use of Semax and Selank Peptides Decoded from LLM-Curated Clinical Notes and Physician Adjudication
Finding14% average quarter-over-quarter growth for Semax.
Human2026Full text read0.80
Quantitative MRI Pharmacokinetic Modeling and MALDI Mass Spectrometry Imaging Biodistribution of a pH Mapping MRI Contrast Agent.
FindingMean pH estimates were cortex 6.86 ± 0.087, outer medulla 6.80 ± 0.073, inner medulla 6.61 ± 0.079.
Animal2026Full text read0.80
[Effect of a combined physiotherapeutic approach on changes in functional parameters after endovitreal surgery of rhegmatogenous retinal detachment with a favorable anatomical outcome].
FindingNot reported in abstract.
Human2026Full text read0.70
Digitally Guided Hybrid Maxillary Expansion with Supragingival Mandibular Miniplates for Class III Correction in Late Adolescents: A Pilot Clinical Study.
FindingMean increase in SNA of +6.1°, p<0.001.
Human2026Full text read0.80
Measuring the Time-Scale-Dependent Information Flow Between Maternal and Fetal Heartbeats During the Third Trimester: Impact of Fetal Sex and Maternal Chronic Stress.
Finding60% coupling strength of maternal decelerations on fetal heart rate complexity.
Human2026Full text read0.80

What people are saying

anecdotal · not evidence

Unverified first-hand accounts from public forums. These are not studies: nobody checked what was taken, whether it was what the label said, or what else was going on. They count for nothing in the evidence grade above and are shown because a reader searching NA Semax Amidate (N-Acetyl Semax Amidate) will meet them anyway, and meeting them next to a graded evidence base is better than meeting them alone.

Community collection has not run yet, so this is an empty shelf rather than a quiet one — nothing has been read, and no conclusion about how much NA Semax Amidate (N-Acetyl Semax Amidate) is discussed should be drawn from it.