NA Semax Amidate (N-Acetyl Semax Amidate) record · updated 20h ago

Neuro & moodHealing & recoveryGrade B · human evidenceResearch use only

All 3 studies Jump to the evidence Compare

What is NA Semax Amidate (N-Acetyl Semax Amidate) used for?

NA Semax Amidate is a modified heptapeptide analog of Semax (ACTH 4-10 fragment) studied for cognitive enhancement, neuroprotection, and BDNF/NGF modulation in preclinical research.

How it works: ACTH(4–10) analog; neuroprotective / nootropic

Primarily researched for · Neuro & moodRoute · Intranasal (research use)

Development stage

where NA Semax Amidate (N-Acetyl Semax Amidate) sits between preclinical work and regulatory approval

1Current
Preclinical
Animal / in-vitro work
2Not reached
Phase 1
Safety in humans
3Not reached
Phase 2
Efficacy signal
4Not reached
Phase 3
Confirmatory trials
5Not reached
Approved
Cleared by a regulator

Stage is inferred from the highest trial phase in the indexed corpus. It describes the research record, not a recommendation.

Identity

NameNA Semax Amidate (N-Acetyl Semax Amidate)

Chain length7 amino acids

Molecular weight855 Da

FormulaC39H54N10O10S

Structure typePeptide

ClassCognitive

Research levelWell Studied

Discovered byCurated master list · 2026

Mass and formula from PubChem CID 172638603. The chain length is only shown where the residues account for that mass, so a figure here has been checked against it rather than taken on trust.

Pharmacology

MechanismACTH(4–10) analog; neuroprotective / nootropic

RouteIntranasal (research use)

Half-life—

Time to peak—

Duration—

Extraction confidence0.50

Effect profile · 0–5

These seven scores are generated by the Librarian — an autonomous agent running GPT-4o over the indexed studies, trials and label data for this compound. No human assigns them and no community vote moves them. Last recomputed Jul 27, 2026. How this works →

Research stats

Total studies3

Human / animal / cellular3 / 0 / 0

Highest trial phase—

Years covered2026

Latest study1mo ago

Publication history

20262026

Research funding

—no NIH grants found

Safety signals

FAERS reportsnone recorded

Serious AEs in animal work—

Community reports—

Positive —Neutral —Negative —

Records

ChEMBL ClinicalTrials.gov DrugBank Google Scholar PubChem PubMed · 3 Semantic Scholar UniProt

Study register

3 rowsOpen in the library →

SortDate added ↓Publication year Evidence type Summary depth

Study	Type	Year	Summary depth
[Effect of a combined physiotherapeutic approach on changes in functional parameters after endovitreal surgery of rhegmatogenous retinal detachment with a favorable anatomical outcome]. FindingNot reported in abstract.	Human	2026	Full text read0.70
Digitally Guided Hybrid Maxillary Expansion with Supragingival Mandibular Miniplates for Class III Correction in Late Adolescents: A Pilot Clinical Study. FindingMean increase in SNA of +6.1°, p<0.001.	Human	2026	Full text read0.80
Measuring the Time-Scale-Dependent Information Flow Between Maternal and Fetal Heartbeats During the Third Trimester: Impact of Fetal Sex and Maternal Chronic Stress. Finding60% coupling strength of maternal decelerations on fetal heart rate complexity.	Human	2026	Full text read0.80

What people are saying

anecdotal · not evidence

Unverified first-hand accounts from public forums. These are not studies: nobody checked what was taken, whether it was what the label said, or what else was going on. They count for nothing in the evidence grade above and are shown because a reader searching NA Semax Amidate (N-Acetyl Semax Amidate) will meet them anyway, and meeting them next to a graded evidence base is better than meeting them alone.

Community collection has not run yet, so this is an empty shelf rather than a quiet one — nothing has been read, and no conclusion about how much NA Semax Amidate (N-Acetyl Semax Amidate) is discussed should be drawn from it.