Ipamorelin

Growth Hormone Secretagogue | Selective GHRP

Research-centric overview

GHWeight Loss

Well Studied

### Summary Ipamorelin is a synthetic peptide that acts as a selective agonist of the growth hormone secretagogue receptor, primarily stimulating growth hormone release. Its potential therapeutic applications are being explored in various contexts, including weight management and pain modulation.

Community effect ratings, structured research logs, and side-effect patterns — all fed by one anonymous form.

Effect profile (overview)

Aggregate AI baseline blended with community voting. Hover to inspect effect strengths per category.

Effect scores blend an AI baseline with community ratings. Open the full chart for per-category detail; rate via the Contribute button.

Research log summary heatmap

Compact view of how logs describe shifts in pain, sleep, and performance (−5 to +5). Treat this as qualitative, anonymous signal only.

No community research logs yet. When structured logs are added, this panel will summarize typical shifts in pain, sleep, and performance.

Anonymous side-effect patterns

Rough heatmap of anonymous side-effect and positive-signal tags — a "most-mentioned" snapshot, not safety or efficacy advice.

No anonymous side-effect reports yet. When reports are submitted, this panel will show a simple heatmap of tags like "nausea", "flushing", "improved healing", and more.

Research footprint

Last analyzed Jul 17, 2026

Studies indexed

Human

Animal

AI analyzed

Evidence mix0% human · 75% animal · 0% cellular · 0% review

Highest phase: PreclinicalYears covered: 2020

Librarian pulse — latest actionsFull changelog ↓

Jul 14, 11:00 PMRe-scoredScored effects for Ipamorelin
Jul 14, 11:00 PMVerifiedVerified content for Ipamorelin: accurate
Jul 13, 7:00 AMVerifiedVerified content for Ipamorelin: accurate

Research & intelligence feed

Studies, clinical trials, community discussions, and news.

Phase II Double-Blind Placebo-Controlled Dose Finding Study to Evaluate Safety/Efficacy of Ipamorelin Compared to Placebo for Recovery of Gastrointestinal Function in Patients Following Small or Large Bowel Resection w/Primary AnastomosisClinical TrialClinicalTrials.govPublished Apr 1, 2011Added Apr 16, 2026

This study evaluated the safety and efficacy of Ipamorelin compared to placebo for recovery of gastrointestinal function in patients following bowel resection with primary anastomosis. The specific dose and outcomes were not detailed in the abstract. The findings may inform future research directions in postoperative recovery.

Phase: PHASE2Status: COMPLETED

A Phase II, Double-Blind, Placebo-Controlled, Multiple-Dose Study to Evaluate the Safety and Efficacy of Ipamorelin Compared to Placebo for the Management of Post-Operative Ileus in PatientsClinical TrialClinicalTrials.govPublished Apr 1, 2008Added Apr 16, 2026

This study evaluated the safety and efficacy of Ipamorelin compared to placebo for managing post-operative ileus in patients. The specifics regarding the dose and outcomes were not detailed in the abstract. The study is classified as a Phase II trial.

Phase: PHASE2Status: COMPLETED

Semantic Scholar search for IpamorelinStudySemanticScholarAdded Dec 12, 2025

Not reported in abstract.

Attenuation of Visceral and Somatic Nociception by Ghrelin Mimetics.StudyPubMedPublished Jan 1, 2020Added Dec 12, 2025

The study explores the potential effects of ghrelin mimetics on pain perception, but specific findings and implications for practice are not detailed.

The influence of ghrelin agonist ipamorelin acetate on the hypothalamic-pituitary-testicular axis in a cichlid fish, Oreochromis mossambicus.StudyPubMedAdded Dec 12, 2025

The study explores the effects of ipamorelin on fish reproductive physiology, but specific findings are not reported in the abstract.

The growth hormone secretagogue receptor 1a agonists, anamorelin and ipamorelin, inhibit cisplatin-induced weight loss in ferrets: Anamorelin also exhibits anti-emetic effects via a central mechanism.StudyPubMedAdded Dec 12, 2025

Not reported in abstract.

External databases

Helpful external resources for additional structural, pharmacologic, and literature context. These are third-party databases; always cross-check details with primary research.

Practical guides for Ipamorelin

How-to and safety articles applicable to every peptide in the library.

Community notes

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Community research logs (detail)

No community research logs yet. Use the “Contribute data” button above to share an anonymized summary of your experience.

Anonymous side-effect reporting (detail)

This section describes how anonymous side-effect reports are aggregated into the heatmap above. Reports are anonymous and unverified, and should be read alongside primary safety data.

Use the "Report side effects" button to open a focused popup form. Please keep descriptions neutral and avoid medical language; think in terms of "nausea", "flushing", "vivid dreams", etc.

Librarian Changelog

Every time the Librarian touches this peptide — discovering, refreshing, scoring, or verifying — it logs the action here.

3d agoScoring70%

Scored effects for Ipamorelin

3d agoVerificationai-researcher90%