Peptides DB
Research-centric peptide and protocol reference hub

Vasopressin record · updated 13h ago

Neuro & moodMetabolic & appetiteGrade A · human clinicalResearch use only
All 43 studiesJump to the evidenceCompare
What is Vasopressin used for?

Research peptide discovered via AI researcher. peptide-based therapeutic

How it works: V1 and V2 receptor agonist

Primarily researched for · Neuro & moodRoute · Subcutaneous injection

Development stage

where Vasopressin sits between preclinical work and regulatory approval
  1. 1Cleared
    Preclinical
    Animal / in-vitro work
  2. 2Cleared
    Phase 1
    Safety in humans
  3. 3Cleared
    Phase 2
    Efficacy signal
  4. 4Cleared
    Phase 3
    Confirmatory trials
  5. 5Current
    Approved
    Cleared by a regulator

Stage is inferred from the highest trial phase in the indexed corpus and 133 registered trials. It describes the research record, not a recommendation.

Identity
NameVasopressin
Chain length—
Molecular weight1,084.2 Da
FormulaC46H65N15O12S2
Structure typeNot established
ClassHealing
Research levelFDA Approved
Discovered byThe Librarian · 2026

Mass and formula from PubChem CID 644077. No verified residue count for this compound.

Pharmacology
MechanismV1 and V2 receptor agonist
RouteSubcutaneous injection
Half-life~10–20 min
Time to peak30–60 min
Duration2–8 hours
Extraction confidence0.90
Effect profile · 0–5
These seven scores are generated by the Librarian — an autonomous agent running GPT-4o over the indexed studies, trials and label data for this compound. No human assigns them and no community vote moves them. Last recomputed Oct 31, 2026. How this works →
Research stats
Total studies43
Human / animal / cellular14 / 12 / 8
Highest trial phasePhase 4
Years covered2011–2026
Latest study6d ago
Publication history
20112026
Research funding
6,325 NIH projects · $24.3M awarded · through FY2026
Public grants naming this compound. Funding is interest, not evidence.
Safety signals
FAERS reports5,911
Serious AEs in animal work—
Community reports—
Positive —Neutral —Negative —
Records

Study register

43 rows · newest 12 shownOpen in the library →
StudyTypeYearSummary depth
Acute colonic pseudo-obstruction with transient failure of oral desmopressin in adipsic arginine vasopressin deficiency.
FindingNot reported in abstract.
Human2023Full text read0.80
Effect of Vasopressin Initiation Threshold on Septic Shock Mortality: The VASSPR Cluster Crossover Randomized Strategy Trial.
FindingMortality at 28 days was 31.8% in the lower-threshold group vs 33.0% in the higher-threshold group, P=0.62.
Human2026Full text read0.90
Vasopressin in Septic Shock-Is Early the Right Question?
TakeawayNot reported in abstract.
—2026Title only0.10
Effect of Vasopressin Initiation Threshold on Septic Shock Mortality: Research Summary.
TakeawayNot reported in abstract.
review2026Title only0.10
Impact of a Capillary Refill Time–Guided Personalised Hemodynamic Resuscitation Protocol in Septic Shock in Low- and Middle-Income Countries: A Post Hoc Analysis of the ANDROMEDA-SHOCK-2 Trial
FindingWin ratio of 1.16 (95% CI 1.14–1.18) in LMICs.
Human2023Full text read0.80
A corticopapillary Gdf15 response links maladaptive collecting duct remodeling to polyuria during lithium exposure
FindingNot reported in abstract.
Human2026Full text read0.70
Manufacturer-Prepared Ready-to-Use versus Traditional IV Piggyback Preparation: A Combined Process-Error, Workforce-Time-Waste, and Cost-Effectiveness Analysis
FindingMP-RTU dominated IVPB in the model, with a base-case incremental cost-effectiveness ratio of −$4,954.15 per additional error avoided.
review2026Full text read0.80
Signaling mechanisms of vasopressin/oxytocin-type neuropeptide-induced muscle contraction in the sea cucumber Apostichopus japonicus.
FindingNot reported in abstract.
In vitro2026Full text read0.70
Hypertension fuels osteoarthritis through neuroendocrine signaling.
FindingNot reported in abstract.
Animal2026Full text read0.70
Oxytocin and Vasopressin Immunoreactivity Differs Across Auditory Brainstem Nuclei in Rodents with Distinct Social Systems
FindingNot reported in abstract.
Animal2026Full text read0.70
Association of Coffee Consumption with Serum Copeptin Levels and Cardiac Diastolic Function in Patients with Autosomal Dominant Polycystic Kidney Disease
FindingCopeptin levels were lower in coffee consumers (262.73 vs. 331.28 ng/L; p = 0.009).
Human2026Full text read0.80
Neuroanatomy of the olfactory bulb of the coyote (Canis latrans): Connection to social information processing
FindingMean glomerular diameter across three individuals is 204.0 ± 20.9 µm.
Animal2026Full text read0.70

What people are saying

anecdotal · not evidence

Unverified first-hand accounts from public forums. These are not studies: nobody checked what was taken, whether it was what the label said, or what else was going on. They count for nothing in the evidence grade above and are shown because a reader searching Vasopressin will meet them anyway, and meeting them next to a graded evidence base is better than meeting them alone.

Community collection has not run yet, so this is an empty shelf rather than a quiet one — nothing has been read, and no conclusion about how much Vasopressin is discussed should be drawn from it.