Research library

D

grade

Not reported in abstract.

summary

C

grade

Dietary supplementation with 600 mg/kg GAA significantly improves growth performance and muscle quality in rainbow trout, as evidenced by increased body weight and enhanced nutrient composition.

72.806 EAAI in the G6 group, P < 0.001.

summary

C

grade

This study describes a new species of Hepatozoon infecting Philodryas nattereri, with all sampled individuals showing parasitism.

100% of specimens were parasitized.

summary

D

grade

Payers recognize the potential of cell and gene therapies but are hindered by high costs and uncertainty about their long-term effectiveness.

Not reported in abstract.

summary

B

grade

Students in a medical program report high knowledge of digital health but low confidence in applying it practically, indicating a need for improved curriculum integration.

131 responses from 848 eligible participants.

summary

B

grade

This case illustrates the diagnostic complexity of esophageal conditions and the challenges in achieving symptom relief despite treatment.

Not reported in abstract.

summary

A

grade

Infigratinib treatment resulted in a statistically significant increase in height velocity in children with achondroplasia over 52 weeks, but the clinical relevance of this change remains to be fully understood.

1.74 cm per year increase in annualized height velocity vs placebo at week 52, 95% CI 1.31 to 2.17, P<0.001

summary

D

grade

Not reported in abstract.

summary

D

grade

Microbiome-based therapies for CDI represent a promising shift towards ecological treatment strategies, but further clinical validation is needed.

summary

C

grade

A dual-targeting strategy shows promise for improving brain delivery and retention of therapeutic antibodies in mice, but human applicability remains to be tested.

Sustained brain concentrations of anti-MOG/TfR antibody for 4 months.

summary

C

grade

A hyaluronic acid-integrated fibrous scaffold shows promise in improving lymphatic function in a rat model of lymphedema, but human studies are needed to confirm its clinical relevance.

Reduced ankle swelling in a rat lymphedema model.

summary

B

grade

Higher estimated glucose disposal rate is associated with lower odds of self-reported endometrial cancer, suggesting a potential link between insulin sensitivity and cancer risk.

Odds ratio for eGDR inversely associated with self-reported EC was 0.906 (95% CI: 0.826-0.991, P = 0.0328)

summary

C

grade

MGF-25E promotes the migration of rat mesenchymal stem cells by activating the CXCR4-ERK1/2 signaling pathway, but the implications for human therapy remain unclear.

Not reported in abstract.

summary

B

grade

Individuals with type 2 diabetes in South Ethiopia navigate complex self-care challenges influenced by economic and cultural factors, highlighting the need for tailored support systems.

summary

A

grade

Elastic tape may enhance pulmonary rehabilitation outcomes in exercise capacity and psychological symptoms for individuals with moderate-to-very severe COPD.

+329s ESWT improvement in ET group, exceeding MCID.

summary

B

grade

NLR, SII, and PDW show some association with endometrial carcinoma but do not reliably distinguish it from premalignant conditions, indicating the need for histopathological evaluation.

Adjusted odds ratio for NLR in EC versus controls was 2.06, 95% CI 1.04-4.09, p=0.037.

summary

C

grade

PSMA-targeted nanobubbles showed improved imaging characteristics in a rabbit model of prostate cancer compared to standard microbubbles, but further research is needed to confirm clinical relevance.

MTT: 4.20 to 5.40-fold higher for PSMA-NBs compared to MBs.

summary

C

grade

The study found that rhH-1 has a 7.5-fold higher linking potency toward hyaluronan and proteoglycans compared to rhH-2, attributed to distinct N-glycosylation differences.

EC50 values of 133.5 ng/mL for rhH-1 and 994.8 ng/mL for rhH-2.

summary

B

grade

CDO1 and ZSCAN12 methylation markers showed strong diagnostic performance for endometrial cancer, with a sensitivity of 97.5% in the evaluated cases.

97.5% sensitivity for EC (39 of 40 evaluable cases)

summary

C

grade

This study highlights the importance of monitoring Listeria monocytogenes in cheese production environments, as persistent strains may form stronger biofilms but do not show increased sanitizer tolerance.

0-6 Single Nucleotide Polymorphisms (SNPs) different.

summary

B

grade

Vaccination counts for meningococcal disease in Türkiye increased significantly in 2025, particularly among infants, and were associated with peaks in public interest and health announcements.

182 children vaccinated between January 2024 and June 2025.

summary

B

grade

Pericardiectomy for constrictive pericarditis carries a 30-day mortality risk of 5.1%, and while long-term survival appears poorer than the general population, this may be influenced by pre-existing comorbidities.

30-day mortality was 5.1%, associated with older age at surgery (p=0.008).

summary

B

grade

The City Birth Trauma Scale shows strong psychometric properties in assessing trauma among Black postpartum women, with 4.6% meeting full PTSD criteria.

α = 0.91 for internal consistency of the BiTS.

summary

D

grade

The study identifies multiple reported pathways for H5N1 transmission to humans, emphasizing the complexity of the virus's transmission routes.

90.8% of sources reported animal-to-human transmission pathways, n=120.

summary

D

grade

Introducing dostarlimab plus CP for endometrial cancer treatment may be budget neutral, but clinical outcomes and efficacy data are not provided.

-$1,650,171 total cumulative budget impact over three years.

summary