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Long-term effectiveness of typhoid conjugate vaccine in Nepal.
IGF-1 LR3 (Long R3 IGF-1) · The Lancet. Global health · 2026Top journal
Not reported in abstract.
Research library
Every indexed study on every peptide in the database, with a machine summary and the numbers that matter pulled out. Filter on the left; the register updates as you go.
1724studies indexed776with human data107registered trials1479carry a numeric findingLibrarian added 0 studies today
Showing 9 studiesSortNewest indexed ▾
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Glomerulus-Targeted Nanotherapy via Collagen IV-α3 Binding Enhances Renal Immunoregulation in Lupus Nephritis.
IGF-1 LR3 (Long R3 IGF-1) · Clinical science (London, England : 1979) · 2026 · Observational
The study suggests that collagen IV-alpha 3 nanoparticles could enhance targeted drug delivery in lupus nephritis, improving renal function metrics.
30% increase in glomerular filtration rate (GFR).
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Long-Term Survival Advantage of Reoperative Surgical Mitral Valve Replacement Over Transcatheter Mitral Valve-in-Valve: A Multicenter Cohort.
IGF-1 LR3 (Long R3 IGF-1) · The Annals of thoracic surgery · 2026 · Observational
Reoperative surgical mitral valve replacement may provide better long-term survival compared to transcatheter mitral valve-in-valve replacement in patients with failing bioprosthetic valves, but treatment decisions should consider both short-term risks and long-term benefits.
20.3% mortality for rSMVR vs 40.9% for mViV at 5 years, P = .01
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Recombinant expression of IGF-1 and LR3 IGF-1 fused with xylanase in Pichia pastoris.
IGF-1 LR3 (Long R3 IGF-1) · PubMed · 2023
The study successfully produced high levels of IGF-1 and LR3 IGF-1 in Pichia pastoris, achieving 0.5 g/L and 1 g/L respectively, but does not provide detailed clinical implications.
0.5 g/L XynCDBFV-IGF-1 and 1 g/L XynCDBFV-LR3 IGF-1 achieved in a 15-L bioreactor.
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Intranasal long R3 insulin-like growth factor-1 treatment promotes amyloid plaque remodeling in cerebral cortex but fails to preserve cognitive function in male 5XFAD mice.
IGF-1 LR3 (Long R3 IGF-1) · PubMed · 2025 · Observational · Preclinical
Intranasal LR3-IGF-1 treatment improved some aspects of amyloid plaque pathology in male 5XFAD mice but did not preserve cognitive function.
Not reported in abstract.
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Zein-Derived Peptides from Corn Promote the Proliferation of C<sub>2</sub>C<sub>12</sub> Myoblasts via Crosstalk of mTORC1 and mTORC2 Signaling Pathways.
IGF-1 LR3 (Long R3 IGF-1) · europepmc · 2024 · Observational · Preclinical
Zein-derived peptides increased C2C12 myoblast cell viability by 33.37 to 42.39% and reduced apoptosis from 34.08% to 28.96%, but these findings are based on in vitro studies.
Cell viability increased by 33.37 to 42.39% with zein peptides at 0.05-0.2 mg/mL.
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Dysfunction of Calcyphosine-Like gene impairs retinal angiogenesis through the MYC axis and is associated with familial exudative vitreoretinopathy.
IGF-1 LR3 (Long R3 IGF-1) · europepmc · 2024 · Observational
The study identifies CAPSL as a potential genetic factor in familial exudative vitreoretinopathy, affecting endothelial cell function and MYC signaling, but does not provide direct clinical implications.
Not reported in abstract.
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Intranasal long R3 insulin-like growth factor-1 treatment promotes amyloid plaque remodeling in cerebral cortex but fails to preserve cognitive function in male 5XFAD mice.
IGF-1 LR3 (Long R3 IGF-1) · europepmc · 2014 · Observational · Preclinical · n=20
LR3-IGF-1 treatment improved some aspects of amyloid pathology in mice but did not preserve cognitive function, indicating limited potential as a standalone therapy.
Not reported in abstract.
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LRP4 and Agrin Are Modulated by Cartilage Degeneration and Involved in β-Catenin Signaling in Human Articular Chondrocytes.
IGF-1 LR3 (Long R3 IGF-1) · europepmc · 2025 · Observational
This study indicates that intense mechanical strain increases Agrin expression, which may disrupt LRP4's role in cartilage health, but further research is needed to understand the clinical implications.
Not reported in abstract.
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