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Effects of Botulinum Toxin Type A and Argireline on Dermal Collagen Remodeling and Skin Biology in a Flap Model.
Argireline · Aesthetic plastic surgery · 2026 · Observational · Preclinical · n=40
BoNT-A alters collagen composition without improving flap survival, and Argireline showed no detectable tissue-level effects in this study.
Flap survival did not differ significantly among groups (p = 0.327).