Dietary tropical seaweed supplementation modulates antioxidant status and immune response in adult Labrador Dogs
Supplementation with G. salicornia and T. conoides may improve certain immune and antioxidant markers in dogs, but the clinical significance of these changes remains uncertain.
Where it sits
this study against the rest of the glutathione (gsh) corpusSummary and findings
This study evaluated the effects of dietary supplementation with tropical seaweeds Gracilaria salicornia and Turbinaria conoides on biochemical parameters, antioxidant status, and immune responses in adult Labrador dogs. Four adult dogs were assigned to four dietary treatments over 21-day experimental periods. The study found significant increases in several immune and antioxidant indices with G. salicornia supplementation.
Abstract
Abstract The present study evaluated the effects of dietary supplementation with the tropical seaweeds Gracilaria salicornia and Turbinaria conoides on blood biochemical parameters, antioxidant status, and immune responses in adult Labrador dogs, using Cichorium intybus (chicory) as a reference functional feed ingredient. A 4 × 4 Latin square design was employed using four adult Labrador Retriever dogs (~ 7 years; BW 16.48 ± 2.63 kg), four dietary treatments, and four experimental periods of 21 days. Dogs in the control group (CON) received a basal diet(NRC 2006), while groups CH, TC, and GS were supplemented with chicory, T. conoides , and G. salicornia , respectively, at 3% dietary dry matter. Hematological and serum biochemical parameters remained within normal physiological ranges and were not significantly affected by dietary treatments (P > 0.05). Serum T3 and T4 concentrations were comparable among treatments, whereas serum cortisol concentrations were significantly lower (P < 0.05) in the GS and TC groups than in the control. Catalase and superoxide dismutase activities were unaffected (P > 0.05); however, supplementation with G. salicornia and T. conoides significantly increased (P < 0.05) glutathione, glutathione peroxidase, ferric reducing antioxidant power,serum IgG, serum IgA, and cell-mediated immune response, while significantly reducing malondialdehyde concentrations. Among the treatments, G. salicornia produced the most consistent improvements in antioxidant and immune indices, indicating its potential as a functional dietary ingredient for adult dogs.
Background
The study appears to investigate the effects of dietary tropical seaweed supplementation on antioxidant status and immune response in adult Labrador dogs. The biological question likely revolves around whether such supplementation can enhance antioxidant defenses and modulate immune function. This research could be significant in understanding dietary interventions for improving health in canines.
Methods
Not reported in abstract.
Results
Not reported in abstract.
Interpretation
Not reported in abstract.
Limitations
- Not reported in abstract.