Peptides DB

Research-centric peptide and protocol reference hub

Neurocognitive & mood exploration

Protocol overview

Exploratory protocol sketch for Selank, Semax, DSIP, and Oxytocin in cognition, sleep, and affect.

Protocol details

Experimental framing of neuropeptide literature. - Focus: attention, stress modulation, sleep architecture, and social bonding - Core agents: Selank, Semax, DSIP, Oxytocin - Caveat: much of the work is small, heterogeneous, or outside large Western trials.

Linked peptides

Peptides that appear in this protocol, with their primary perceived effect profiles.

SelankPeptide

### Selank Summary Selank is a synthetic peptide derived from the naturally occurring peptide tuftsin, primarily studied for its potential anxiolytic and cognitive-enhancing properties. Research into Selank has focused on its effects on neuroprotection, stress response, and cognitive function, although further studies are needed to fully understand its mechanisms and therapeutic applications.

SemaxPeptide

### Summary Semax is a synthetic peptide derived from the adrenocorticotropic hormone (ACTH) that has been investigated for its potential neuroprotective and cognitive-enhancing effects. Research suggests that Semax may influence various biological pathways, including neuroinflammation and intracellular calcium dynamics.

DSIPPeptide

Delta Sleep-Inducing Peptide, primarily discussed for sleep quality, stress modulation, and pain.

OxytocinPeptide

### Oxytocin Summary Oxytocin is a neuropeptide that plays a crucial role in social bonding, reproductive behaviors, and emotional regulation. Its functions extend to various physiological processes, including childbirth and lactation, and it has garnered interest for its potential therapeutic applications in mental health and social disorders.

Community tags (where this is used)

Lightweight, anonymous voting on where this protocol tends to show up in people's research (not recommendations or medical guidance).

Community stacks, dosing & cycles

Anonymous, research-framed suggestions for how people structure this protocol in practice. No medical advice; use as inspiration, then cross-check against primary evidence.

Filter variants:

No community variants logged yet. The sample row below is illustrative until real submissions appear.

VariantStackDosageCycleSubmittedUpvotes
Sample: 8-week tendon stack (example)
Illustrative structure only. Replace with real-world, research-framed variants once community submissions are available.
BPC-157 + TB-500 + progressive PT 3x/week; sleep and protein focus
e.g. BPC-157 ~250 mcg daily, TB-500 twice weekly
8–12 weeks, then reassess / deload

Research & studies for this protocol

Semantic Scholar search for DSIPSemanticScholarDSIP

Not reported in abstract.

Semantic Scholar search for SemaxSemanticScholarSemax

Not reported in abstract.

Semantic Scholar search for SelankSemanticScholarSelank

Not reported in abstract.

Semantic Scholar search for OxytocinSemanticScholarOxytocin

Not reported in abstract.

Modulation of neuropathological pathways by bioactive peptides and proteins/polypeptides: Targeting oxidative stress in neurodegenerative diseases.PubMedSemax

This study investigates the modulation of neuropathological pathways by bioactive peptides, specifically focusing on oxidative stress in neurodegenerative diseases. The specific peptide examined is Semax, though details regarding dosage and population are not provided. The findings suggest potential pathways affected by Semax, but no therapeutic claims are made.

The Effect of Peptide Semax, an ACTH(4-10) Analogue, on Intracellular Calcium Dynamics in Rat Brain Neurons.PubMedSemax

This study investigated the effect of the peptide Semax on intracellular calcium dynamics in rat brain neurons. The specific doses and detailed outcomes were not reported in the abstract. The findings may contribute to understanding the peptide's role in neuronal function.

Effect of ACTH4-10Pro8-Gly9-Pro10 on anti-inflammatory cytokine (IL-4, IL-10, IL-13) expression in acute spinal cord injury models (male Sprague Dawley rats).PubMedSemax

This study evaluated the effect of ACTH4-10Pro8-Gly9-Pro10 on the expression of anti-inflammatory cytokines (IL-4, IL-10, IL-13) in acute spinal cord injury models using male Sprague Dawley rats. The specific doses and outcomes were not detailed in the abstract. The findings may contribute to understanding the peptide's role in inflammatory responses following spinal cord injury.

Effect of perioperative ONS combined with intestinal microecology in patients with colorectal cancer: a randomized clinical trial.PubMedSelank

This study measured the effect of perioperative oral nutritional supplementation (ONS) combined with intestinal microecology on patients with colorectal cancer. The specific doses and outcomes were not detailed in the abstract. The study's findings are relevant for understanding nutritional interventions in surgical patients.

A study of the correlation between urinary perchlorate, nitrate, thiocyanate, and serum liver function indices.PubMedSelank

Not reported in abstract.

Efficiency in packed red blood management for brain tumor resection: multicentre prospective cohort study (TScoreBTR).PubMedSelank

Not reported in abstract.

Oxytocin administration during labor does not affect maternal serum oxytocin levels, early postpartum breastfeeding attitude and maternal attachment.PubMedOxytocin

This study examined the effects of oxytocin administration during labor on maternal serum oxytocin levels, early postpartum breastfeeding attitude, and maternal attachment. The population studied was not specified in the abstract. Not reported in abstract.

Postpartum Hemorrhagic Morbidities With Livebirth versus Stillbirth.PubMedOxytocin

This study examines postpartum hemorrhagic morbidities associated with livebirth versus stillbirth. The specific outcomes measured include various hemorrhagic complications in the postpartum period. Not reported in abstract.

"Anxiety and worry" induces fear transformation in cancer patients: an evidence-based exploration and theoretical consideration of the emotional evolution in tumor patients.PubMedOxytocin

This study explores the relationship between anxiety, worry, and fear transformation in cancer patients. The specific doses of oxytocin administered and the exact outcomes measured are not detailed in the abstract. The findings aim to provide insights into the emotional evolution of patients with tumors.

Sensing the Bactericidal and Bacteriostatic Antimicrobial Mode of Action Using Raman Deuterium Stable Isotope Probing (DSIP) in Escherichia coli.PubMedDSIP

This study investigates the antimicrobial effects of Deuterium Stable Isotope Probing (DSIP) on Escherichia coli. The specific outcomes measured include bactericidal and bacteriostatic actions. Not reported in abstract.

Pichia pastoris secreted peptides crossing the blood-brain barrier and DSIP fusion peptide efficacy in PCPA-induced insomnia mouse models.PubMedDSIP

This study investigates the efficacy of DSIP fusion peptides in a mouse model of insomnia induced by PCPA. The peptides were secreted by Pichia pastoris and their ability to cross the blood-brain barrier was assessed. No therapeutic claims are made regarding the effects observed.

Domain-specific information preservation for Alzheimer's disease diagnosis with incomplete multi-modality neuroimages.PubMedDSIP

This study investigates the use of domain-specific information preservation for diagnosing Alzheimer's disease using incomplete multi-modality neuroimages. The specific metrics and outcomes measured in relation to DSIP are not detailed in the abstract. The findings may have implications for diagnostic methodologies in Alzheimer's disease.