Research library

C

grade

Oxytocin can elevate neuronal excitability in VTA dopaminergic neurons in PTSD model rats, but baseline activity remains lower compared to controls.

Not reported in abstract.

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B

grade

Lower peripheral OXTR DNAm levels may be associated with higher symptom severity in panic disorder, but the implications for treatment and clinical practice remain uncertain.

Not reported in abstract.

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C

grade

Chemogenetic activation of oxytocin neurons in macaques appears to enhance gaze toward the eyes during face exploration, suggesting a role for these neurons in social visual orienting.

Not reported in abstract.

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B

grade

Oxytocin can induce significant perfusion changes in uterine fibroids, which may help predict the efficacy of HIFU treatment.

APDT(Δt) was significantly longer in the ≥70% group at 16.76 ± 12.12 s, p<0.05.

summary

A

grade

Intrauterine oxytocin-soaked gauze during cesarean delivery significantly reduces blood loss and supports maternal stability without added complications.

Median blood loss was 440 mL [IQR 350–530] in the oxytocin group compared with 540 mL [420–625] in the saline group and 625 mL [475–700] in the control group; p<0.001.

summary

B

grade

Perinatal depression may involve various epigenetic alterations linked to stress and hormonal changes, but more research is needed to clarify these relationships and their clinical implications.

Not reported in abstract.

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A

grade

Oromucosal administration of 48 IU of oxytocin may increase attention to social stimuli in men, while atosiban appears to reduce this preference.

48 IU oxytocin significantly increased preferential viewing of social stimuli relative to placebo, n=250.

summary

B

grade

Perinatal depression may involve various epigenetic alterations related to stress and hormonal changes, but more research is needed to confirm these findings and their clinical implications.

Not reported in abstract.

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B

grade

NSAIDs are the most effective treatment for reducing menstrual pain and uterine contractions in dysmenorrhea, but other therapies require further evaluation.

Not reported in abstract.

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B

grade

A predictive model for abnormal fetal heart rate patterns during labor epidural analgesia showed good discrimination and calibration, but further validation is needed.

The nomogram's AUC was 0.800.

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B

grade

Young women with high perceived stress show distinct inflammatory profiles and lower BDNF levels, indicating a potential link between chronic stress and inflammation.

4E-BP1 log2FC = 0.565 in high perceived stress group.

summary

C

grade

This study indicates that sex differences in the oxytocinergic system may arise from testosterone-dependent epigenetic mechanisms during early brain development.

Not reported in abstract.

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C

grade

This study highlights the role of HIF-1 and other signaling pathways, including oxytocin, in breast cancer, suggesting they may inform future combination therapies.

Not reported in abstract.

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B

grade

Emergency obstetric and newborn care readiness in Ethiopia shows substantial geographical variation, with higher readiness in general hospitals compared to medium clinics. Oxytocin availability is positively associated with facility readiness.

Mean CERI was 57.4 (SE 2.6).

summary

B

grade

The integration of heat-stable carbetocin into routine maternal care achieved high coverage and timely administration, with a lower incidence of postpartum hemorrhage compared to oxytocin in this observational study.

200 PPH cases (0.48%) among women receiving HSC prophylaxis.

summary

C

grade

Dog behaviors traditionally viewed as stress indicators may not be reliable, as their meaning can vary based on individual attachment styles and context.

Oxytocin correlated positively with lip-licking in securely attached dogs (p < 0.05), but negatively in anxious ones (p < 0.05)

summary

B

grade

Mifepristone priming may lead to a shorter induction-to-delivery interval and less pain compared to Foley’s catheter for labor induction in cases of IUFD beyond 24 weeks.

Mean induction-to-delivery interval was 25.43±6.84 hours in Group A vs 29.26±5.54 hours in Group B; p=0.0014.

summary

B

grade

Castor oil plus membrane sweeping may be a safe and effective alternative to misoprostol for labor induction, with potential benefits in reducing secondary medical interventions.

59.2% achieved labor onset within 24 hours in the non-pharmacological group vs. 56.1% in the misoprostol group.

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D

grade

The review found that interactions between oxytocin and sex hormones are infrequently observed and lack robust evidence, highlighting the need for improved methodologies in future research.

Not reported in abstract.

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A

grade

Oxytocin may reduce subjective fear responses during high-stress situations, but its clinical implications require further investigation.

Not reported in abstract.

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C

grade

The study highlights the importance of specific neuronal activity patterns in social fear extinction, suggesting potential avenues for addressing treatment-resistant social anxiety disorder.

Not reported in abstract.

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C

grade

This study demonstrates a new method for precise delivery of oxytocin in the brain using light-controlled nanovesicles, which could enhance our understanding of neuropeptide functions.

Near-complete release achievable within a ~2-hour window.

summary

D

grade

Not reported in abstract.

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C

grade

Limosilactobacillus reuteri supplementation may help mitigate some behavioral deficits associated with PBDE exposure in mice, but the relevance to human health is unclear.

LR treatment increased plasma total thyroxine in DE-71 and plasma OXT in VEH/CON dams.

summary

B

grade

Cessation of oxytocin during the active phase of induced labor did not reduce caesarean delivery rates in this study, and maternal satisfaction decreased modestly after the policy change.

Caesarean delivery occurred in 29% of women before and 28% after policy implementation (p=0.77).

summary