Peptides DB
Research-centric peptide and protocol reference hub

Research library

Every indexed study on every peptide in the database, with a machine summary and the numbers that matter pulled out. Filter on the left; the register updates as you go.

2255studies indexed1010with human data129registered trials1946carry a numeric findingLibrarian added 23 studies today
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Genome-integrated engineering of <i>Escherichia coli</i> Nissle 1917 enables sustained gut-local biosynthesis of 5-hydroxytryptophan.
Ecnoglutide · Synthetic and systems biotechnology · 2026 · Observational · Preclinical
The engineered probiotic strain achieved a 5-HTP titer of 863.2 mg/L and showed potential for gut-local biosynthesis, but findings are based on mouse models and may not directly translate to humans.
5-HTP titer of 863.2 mg/L, the highest level reported in EcN-based systems.
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Efficacy and safety of cAMP signalling-biased GLP-1 analogue ecnoglutide monotherapy versus placebo in patients with type 2 diabetes (EECOH-1): a randomised, double-blind, placebo-controlled, phase 3 trial
Ecnoglutide · biorxiv-preprint · 2025 · RCT
Ecnoglutide showed a statistically significant reduction in HbA1c and body weight compared to placebo in a 24-week trial, but the clinical relevance of these findings requires further evaluation.
-1.96% HbA1c vs placebo at 24 wk with 0.6 mg ecnoglutide, n=69.
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