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Study 3 of 7Argireline literaturePubMed · Observational2024

INDIVIDUAL ARTICLE: Real-World Clinical Experience With a Neuro-Peptide Serum in Combination With Botulinum Toxin Type-A Injections.

The combination of a neuro-peptide serum with BTX-A injections may improve cosmetic outcomes, but the evidence is based on practitioner experiences rather than controlled studies.

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Where it sits

this study against the rest of the argireline corpus
1
Preclinical
6
Observational · this one
0
Open-label
0
Randomised
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Summary and findings

This study evaluated the experiences of 5 dermatologists and 2 surgeons using a topical neuro-peptide serum in combination with botulinum toxin type-A injections. The serum contained 2% acetyl hexapeptide-8, 2% dipeptide diaminobutyroyl, 5% polyhydroxy acids, 5% niacinamide, and 1% laminaria extract. No specific numeric outcomes or statistical analyses were reported in the abstract.

How much of this paper we could read: title only (0.30). The feed gave us little more than the title, so our summary is thin. This says nothing about the study's quality — read the source. What this means →
2024

Abstract

The authors’ words, as PubMed supplied them

We evaluated real-life experiences of a topical neuro-peptide serum containing 2% acetyl hexapeptide-8, 2% dipeptide diaminobutyroyl, 5% polyhydroxy acids (PHA), 5% niacinamide, and 1% laminaria extract (topical neuro-peptide serum [TNP-serum]). The TNP-serum works synergistically by stimulating 9 key skin biomarkers to reduce wrinkles and produce a skin-brightening effect. Here, we highlight the real-life experiences of 5 dermatologists and 2 surgeons, using an integrated skincare regimen consisting of botulinum toxin type-A (BTX-A) injection in conjunction with twice daily TNP-serum. Real-world cases provide evidence for combination treatments that may be used in cosmetic dermatology to improve patient outcomes and satisfaction. TNP-serum appears to complement BTX-A injections to improve radiance, reduce fine lines, and reduce wrinkles in diverse patients. Incorporating TNP-serum into integrated skincare regimens may offer an additive effect to BTX-A injections and, ultimately, optimize patient results. J Drugs Dermatol. 2024;23:11(Suppl 2):s3-14.

Background

The paper addresses the clinical application of a neuro-peptide serum alongside Botulinum Toxin Type-A, which is commonly used for aesthetic purposes. Prior studies have suggested that such combinations may enhance the effects of the toxin, but comprehensive data on their efficacy and safety in real-world settings is limited. This study aims to fill that gap by providing insights from clinical practice.

Methods

Not reported in abstract.

Results

Not reported in abstract.

Interpretation

Not reported in abstract.

Key findings

  • Not reported in abstract.

Limitations

  • Not reported in abstract.

Elsewhere in the Argireline corpus

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