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Study 14 of 14BPC-157 literatureDEN open · Case report2023

First Case Report of Triple Recurrent Cholangitis of "Coildocholithiasis," Following Hepatic Artery Pseudoaneurysm Embolization.

This case report highlights the rare but serious complication of coil migration leading to recurrent cholangitis after embolization treatment.

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Where it sits

this study against the rest of the bpc-157 corpus
3
Preclinical
9
Observational · this one
0
Open-label
0
Randomised
2
Reviews

Summary and findings

A 72-year-old man experienced three episodes of cholangitis due to coil migration following treatment for a hepatic artery pseudoaneurysm. The patient underwent transcatheter arterial embolization with tornado microcoils. This case highlights the complications associated with coil migration into the bile duct.

How much of this paper we could read: full text read (0.80). We had a clear abstract, so the summary below closely tracks the paper. What this means →
Not reported in abstract.n=12023

Abstract

The authors’ words, as DEN open supplied them

A 72-year-old man developed a hepatic artery pseudoaneurysm (HAP) caused by a liver abscess due to acute cholangitis and choledocholithiasis. He was successfully treated by transcatheter arterial embolization (TAE) with tornado microcoils. Two years later, he developed severe acute cholangitis caused by a biliary stone formed around a coil that had migrated into the common bile duct, termed "Coildocholithiasis." The stone was removed successfully, while several coils remained in the liver. He subsequently experienced repeated "Coildocholithiasis" and cholangitis, and after the third episode of coil migration, no coil remained in the liver. Since HAP can be fatal if it ruptures, TAE has become a standard treatment for HAP and other arterial aneurysms. Coil migration to other organs is a rare late-onset complication. This is the first report of three consecutive coil migrations in one patient, discussing the mechanisms of migration and whether prophylactic endoscopic removal should be considered once asymptomatic coil migration into the bile duct is identified.

Background

This paper addresses the clinical implications of coil migration following transcatheter arterial embolization for hepatic artery pseudoaneurysm. Previous literature has documented complications associated with coil embolization, but this case uniquely reports multiple episodes of cholangitis due to coil migration. Understanding these complications is essential for improving patient management and outcomes.

Methods

This is a case report detailing the clinical course of a 72-year-old male patient who underwent transcatheter arterial embolization for a hepatic artery pseudoaneurysm. The report describes the patient's subsequent episodes of cholangitis related to coil migration. No specific n, dose, or duration is provided in the abstract.

Results

The patient developed severe acute cholangitis due to a biliary stone formed around a coil that migrated into the common bile duct. He experienced three episodes of coil migration, with the last episode resulting in no coils remaining in the liver. Specific numeric findings are not reported.

Interpretation

This case adds to the limited literature on the complications of coil embolization, particularly regarding repeated coil migrations leading to cholangitis. While the findings are significant in highlighting a rare complication, the clinical relevance may be limited due to the singular nature of the case and lack of broader population data. The absence of detailed numeric outcomes restricts the ability to assess the clinical impact fully.

Key findings

  • Patient developed severe acute cholangitis due to biliary stone formed around a migrated coil.
  • First report of three consecutive coil migrations in one patient.
  • Coil migration to other organs is a rare late-onset complication.

Limitations

  • Single patient case report.
  • No numeric outcomes reported.
  • Lack of comparative data.
  • Not a controlled study.

Elsewhere in the BPC-157 corpus

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