Evaluating Seismocardiography as a Non-Exercise Method for Estimating Maximal Oxygen Uptake.
The Seismofit® sensor correlates well with traditional VO2MAX measurements from CPET, but its clinical application in diverse populations remains to be validated.
Where it sits
this study against the rest of the vilon (ke) corpusSummary and findings
This study evaluated the Seismofit® sensor for estimating maximal oxygen uptake (VO2MAX) in a cohort of 94 healthy subjects. Participants underwent cardiopulmonary exercise testing (CPET) alongside Seismofit® measurements taken before and after exercise. The findings indicated a correlation between CPET and Seismofit® estimates.
Abstract
<h4>Background</h4>The value of maximal oxygen uptake (VO<sub>2MAX</sub>) is a key health indicator. Usually, VO<sub>2MAX</sub> is determined with cardiopulmonary exercise testing (CPET), which is cumbersome and time-consuming, making it impractical in many testing scenarios. The aim of this study is to validate a novel seismocardiography sensor (Seismofit<sup>®</sup>, VentriJect DK, Hellerup, Denmark) for non-exercise estimation of VO<sub>2MAX</sub>.<h4>Methods</h4>A cohort of 94 healthy subjects (52% females, 48.2 (8.7) years old) were included in this study. All subjects performed an ergometer CPET. Seismofit<sup>®</sup> measurements were obtained 10 and 5 min before CPET in resting condition and 5 min after exhaustion.<h4>Results</h4>The CPET VO<sub>2MAX</sub> was 37.2 (8.6) mL/min/kg, which was not different from the two first Seismofit<sup>®</sup> estimates at 37.5 (8.1) mL/min/kg (<i>p</i> = 0.28) and 37.3 (7.8) mL/min/kg (<i>p</i> = 0.66). Post-exercise Seismofit<sup>®</sup> was 33.8 (7.1) mL/min/kg (<i>p</i> < 0.001). The correlation between the CPET and the Seismofit<sup>®</sup> was r = 0.834 and r = 0.832 for the two first estimates, and the mean average percentage error was 11.4% and 11.2%. Intraclass correlation coefficients between the first and second Seismofit<sup>®</sup> measurement was 0.993, indicating excellent test-retest reliability.<h4>Conclusion</h4>The novel Seismofit<sup>®</sup> VO<sub>2MAX</sub> estimate correlates well with CPET VO<sub>2MAX</sub>, and the accuracy is acceptable for general health assessment. The repeatability of Seismofit<sup>®</sup> estimates obtained at rest was very high.
Background
The study addresses the challenge of estimating maximal oxygen uptake (VO2MAX), a critical health indicator typically measured through cardiopulmonary exercise testing (CPET). CPET is often impractical due to its complexity and time requirements. This research aims to validate a non-exercise method using a seismocardiography sensor, which could provide a more accessible means of estimating VO2MAX.
Methods
This study involved a cohort of 94 healthy subjects, with a demographic breakdown of 52% females and an average age of 48.2 (8.7) years. Each participant underwent an ergometer CPET, while Seismofit® measurements were taken at rest 10 and 5 minutes before the test and 5 minutes after exhaustion. The primary outcome was the correlation between VO2MAX values obtained from CPET and Seismofit®.
Results
The primary endpoint indicated that CPET VO2MAX was 37.2 (8.6) mL/min/kg. The first and second Seismofit® estimates were 37.5 (8.1) mL/min/kg (p=0.28) and 37.3 (7.8) mL/min/kg (p=0.66), respectively. The post-exercise Seismofit® measurement was significantly lower at 33.8 (7.1) mL/min/kg (p<0.001). Correlation coefficients between CPET and Seismofit® were r = 0.834 and r = 0.832, with mean average percentage errors of 11.4% and 11.2%.
Interpretation
The findings suggest that the Seismofit® sensor provides a reasonable estimate of VO2MAX compared to CPET, with high correlation coefficients. However, the clinical significance of the differences observed, particularly the post-exercise values, may be limited. The study's reliance on a healthy population and the absence of diverse subject profiles may restrict the applicability of the results. Thus, while the method shows promise, further research is needed to establish its utility in broader clinical contexts.
Key findings
- CPET VO2MAX was 37.2 (8.6) mL/min/kg, n=94.
- First Seismofit® estimate was 37.5 (8.1) mL/min/kg, p=0.28.
- Second Seismofit® estimate was 37.3 (7.8) mL/min/kg, p=0.66.
- Post-exercise Seismofit® was 33.8 (7.1) mL/min/kg, p<0.001.
- Correlation between CPET and Seismofit® was r = 0.834 and r = 0.832 for the two first estimates.
- Mean average percentage error was 11.4% and 11.2%.
Limitations
- limited to healthy subjects, n=94
- short follow-up after exercise
- correlation does not imply causation
- no diverse population studied