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Study 9 of 16Glutathione (GSH) literatureDEN open · Case report2023

Small-Bowel Impaction Caused by Mechanical Interlocking Between Duodenal Metal and Biliary Plastic Stents.

Clinicians should be aware that mechanical interlocking between duodenal SEMS and biliary PS can lead to small-bowel impaction, necessitating careful follow-up and potential intervention.

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Preclinical
13
Observational · this one
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Open-label
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Randomised
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Summary and findings

This case report discusses a 78-year-old woman with pancreatic head cancer who experienced small-bowel impaction due to the migration of a duodenal self-expandable metal stent (SEMS) interlocked with a biliary plastic stent (PS). The patient underwent a partial ileal resection after unsuccessful attempts to remove the stents via double-balloon enteroscopy. Histopathological examination indicated transmural infiltration of inflammatory cells and abscess formation.

How much of this paper we could read: full text read (0.80). We had a clear abstract, so the summary below closely tracks the paper. What this means →
Not reported in abstract.n=12023

Abstract

The authors’ words, as DEN open supplied them

Duodenal self-expandable metal stents (SEMS) are widely used to treat malignant gastric outlet obstruction (GOO). However, stent migration is a well-known complication. We report a rare case of small-bowel impaction caused by the migration of a duodenal SEMS with a biliary plastic stent (PS). A 78-year-old woman with pancreatic head cancer underwent biliary PS and duodenal SEMS placement for obstructive jaundice and GOO. At 4 months after initiating neoadjuvant chemotherapy, computed tomography revealed tumor shrinkage and improvement in duodenal stenosis; however, the SEMS and PS had migrated to the ileum. Double-balloon enteroscopy was attempted; however, stent removal was unsuccessful because of mechanical interlocking and impaction. Therefore, a partial ileal resection was performed. Histopathological examination revealed transmural infiltration of inflammatory cells and abscess formation. If a duodenal SEMS migrates with a biliary PS, mechanical interlocking may occur, resulting in small-bowel impaction. Clinicians should be aware of this rare complication and should consider careful follow-up and timely intervention if stent migration is detected. <b>Trial Registration</b>: N/A.

Background

This paper addresses the complications associated with the use of duodenal self-expandable metal stents (SEMS) in patients with malignant gastric outlet obstruction (GOO). Prior knowledge indicates that stent migration is a recognized complication, but the specific issue of mechanical interlocking with biliary plastic stents (PS) has not been widely reported. Understanding such complications is critical for improving patient management and outcomes in similar clinical scenarios.

Methods

This is a case report involving a 78-year-old female patient with pancreatic head cancer who underwent biliary PS and duodenal SEMS placement. The paper does not specify the exact doses or techniques used for stent placement. The primary outcome was the occurrence of small-bowel impaction due to stent migration.

Results

The SEMS and PS migrated to the ileum, leading to small-bowel impaction. Attempts at stent removal via double-balloon enteroscopy were unsuccessful due to mechanical interlocking. A partial ileal resection was performed, and histopathological examination revealed transmural infiltration of inflammatory cells and abscess formation.

Interpretation

This case highlights a rare but significant complication of stent migration and mechanical interlocking, which may not be widely recognized in the literature. The findings underscore the importance of careful monitoring and timely intervention in patients with stents. However, the lack of broader data limits the ability to generalize these findings to the wider population of patients with similar conditions.

Key findings

  • At 4 months after initiating neoadjuvant chemotherapy, computed tomography revealed tumor shrinkage and improvement in duodenal stenosis.
  • The SEMS and PS had migrated to the ileum.
  • Stent removal was unsuccessful because of mechanical interlocking and impaction.

Limitations

  • This is a case report with no control group.
  • Single patient experience limits generalizability.
  • No statistical analysis provided.
  • Short follow-up period may not capture long-term outcomes.

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