Research library

B

grade

The updated Saudi guidelines recommend PASI 90 as the primary treatment goal for psoriasis and advocate for the use of biologic therapies in both adults and children.

Not reported in abstract.

summary

D

grade

Natural products show promise in targeting HBx and associated pathways in HBV-related HCC, but clinical validation is needed.

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B

grade

Structured school-based health education can significantly improve students' knowledge about zoonotic diseases, particularly through engaging methods like board games.

Knowledge of zoonoses increased from 15.7% to 56.6%, p<0.05.

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D

grade

The true burden of Clostridioides difficile in West Africa remains unclear, highlighting the need for improved diagnostics and research.

Not reported in abstract.

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B

grade

Invasive fungal infections are common and significantly increase mortality risk in patients with mature T-cell and NK-cell lymphomas.

21% of patients developed 52 IFI episodes, n=203.

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B

grade

APMV-1 can potentially cause severe pneumonia in humans, highlighting the need for better surveillance of zoonotic diseases.

40 APMV-1 sequence reads (50.6% microbial abundance) covering 10.78% of the genome.

summary

C

grade

Supplementing layer pullet diets with a Bacillus-based probiotic may lead to a temporary reduction in Salmonella Enteritidis levels in the gut, but it does not appear to affect systemic infection rates.

Cecal SE counts reduced by 1.22 log₁₀ CFU/g in probiotic-fed birds at 10 dpi, n=192, P=0.0154.

summary

B

grade

The mt-sDNA colorectal cancer screening program is cost-effective compared to no screening, with an ICER of CNY 43,627 per QALY gained.

ICER of mt-sDNA screening was CNY 43,627 per QALY gained.

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B

grade

Web-based surveys can be more efficient but may yield different results than telephone surveys, highlighting the need for careful consideration of sample representativeness.

aOR=0.71, 95% CI 0.61-0.82 for severe adulthood physical violence in web survey.

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C

grade

Thermal wounding of the Venus flytrap's petiole can trigger electrical activity in the trap, but the implications for prey capture mechanisms require further investigation.

Not reported in abstract.

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C

grade

Combining phytase with xylanase-β-glucanase can help improve gut health and growth performance in young broilers fed high-fiber diets.

NC increased ileal and jejunal digesta viscosity, <i>P</i> < 0.05.

summary

B

grade

Food insecurity is prevalent among refugees in Uganda, particularly in larger and female-headed households, highlighting the need for targeted interventions.

84.7% of households were food insecure, n=600.

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B

grade

The controlled temperature chain (CTC) for oral cholera vaccine deployment allows storage at ambient temperatures for up to 14 days, potentially improving logistics and reducing costs.

Vaccines could be stored at ambient temperatures for up to 14 d under CTC.

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B

grade

FMF from active ulcerative colitis patients can induce a strong pro-inflammatory response in an intestine-on-chip model, but the clinical implications remain to be fully understood.

Not reported in abstract.

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A

grade

Dersimelagon appears to be well tolerated in healthy participants, with notable increases in melanin density at certain doses, but further research is needed to assess its effects in patients with EPP and XLP.

Mean t_1/2 ranged from 10.56 to 18.97 hours on day 14.

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C

grade

The MC4RF51L mutation in mice shows a specific defect in Gq/11α signaling, leading to obesity and hyperphagia, suggesting new avenues for obesity treatment research.

Not reported in abstract.

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C

grade

This study indicates that α-MSH may protect against cardiac remodeling in mice, but further research is necessary to determine its relevance in humans.

Not reported in abstract.

summary