Research library

B

grade

The study found that young men had a significantly greater GH response to GHRH and GHRP-2 compared to older men, with abdominal fat negatively impacting GH release.

1.4-fold more GH release with l-arginine/GHRH in young than older men, P = 0.021.

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A

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This study found that gender and sex-steroid supplementation significantly affect growth hormone recovery from autoinhibition, with distinct effects based on the type of secretagogue used.

Nadir GH and peak GH during feedback were enhanced by GHRH or GHRP-2 (P < 0.001 for both).

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B

grade

The proportion of carbapenem-resistant hypervirulent Klebsiella pneumoniae in Türkiye rose from 20.7% to 33.1% between 2018 and 2023, with a notable shift to ST147 as the dominant lineage.

33.1% CR-hvKp among CR-Kp by 2023.

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B

grade

Overweight patients with non-functioning pituitary tumors may have a significantly higher risk of severe growth hormone deficiency, indicating the need for targeted diagnostic approaches.

Overweight (odds ratio, 3.86; 95% confidence interval, 1.02-14.66).

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C

grade

AG and DAG have different effects on feed intake and growth in broiler chickens, with AG decreasing these parameters and DAG increasing them.

Linear decrease in FI with AG infusion, P=0.002.

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B

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This study found that lower growth hormone levels are associated with higher inflammatory markers, but the clinical implications of this relationship remain unclear.

Peak GH significantly and negatively predicted hs-CRP levels (β = -0.345; 95% CI, -0.533 to -0.158).

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B

grade

Clinicians should consider the possibility of adrenal insufficiency in patients who have received immune checkpoint inhibitors like pembrolizumab, especially when nonspecific symptoms arise during or after chemotherapy.

Not reported in abstract.

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B

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Patients receiving PD-1/CTLA-4 antibody therapy have a significantly higher risk of multiple pituitary hormone deficiencies compared to those on PD-1 monotherapy.

Pituitary irAEs incidence: 16/74 (21.6%) vs. 25/748 (3.3%), P<0.001

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B

grade

This case highlights the diagnostic complexities of managing hyponatremia in COVID-19, suggesting that adrenal insufficiency should be considered alongside SIADH.

Not reported in abstract.

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B

grade

In cases of acute Sheehan syndrome with persistent hyponatremia despite hydrocortisone treatment, consider evaluating for inappropriate AVP secretion dynamics.

Not reported in abstract.

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