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Neoagarotetraose from Marine Red Algae Attenuates Hypertensive Vascular Remodeling by Targeting FoxO4 to Inhibit Mitochondrial Superoxide Generation.
FOXO4-DRI (FOXO4-D-Retro-Inverso) · Journal of agricultural and food chemistry · Observational · Preclinical
NA4 may reduce oxidative stress and lower blood pressure in hypertensive rats, but its effects in humans are not established.
NA4 lowered blood pressure in SHR after 4 weeks of oral administration at doses of 200 or 250 mg/kg/day.