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An orthogonal transcription system enables high-efficiency rescue of measles virus-based vaccine vectors against multiple pathogens.
CJC-1295 without DAC (Modified GRF 1-29) · Synthetic and systems biotechnology · 2026 · Animal study · Preclinical
The new orthogonal transcription system significantly enhances the efficiency of rMeV vector rescue, showing promise for rapid vaccine development, though human studies are needed.
Rescue efficiency enhanced by more than 50-fold.