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Anti-Inflammatory Effects of Clarstatin, a Shared-Epitope-Antagonistic Cyclic Peptide, on Experimental Autoimmune Uveitis in Mice.
Cibinetide · Investigative ophthalmology & visual science · 2025 · Observational · Preclinical
Clarstatin showed a significant reduction in inflammation in mouse models of uveitis, but its relevance to human treatment remains to be established.
30% to 80% decrease in clinical score, P < 0.05.