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Relaxin for the treatment of patients with acute heart failure (Pre-RELAX-AHF): a multicentre, randomised, placebo-controlled, parallel-group, dose-finding phase IIb study.
B7-33 (Relaxin) · Lancet (London, England) · 2009 · RCTTop journal
Relaxin may improve dyspnoea and reduce hospital stay in patients with acute heart failure, but further studies are needed to confirm these findings.
40% of patients in the relaxin 30 microg/kg group moderately or markedly improved dyspnoea at 6 h, 12 h, and 24 h vs 23% in the placebo group, p=0.044.