C
grade
Pharmacological inhibition of TRPM4 channel stabilizes atherosclerotic plaque via inhibiting AMPK-Beclin1-mediated autophagy.
AICAR (Acadesine) · PubMed · 2026 · Observational · Preclinical
The study indicates that TRPM4 may contribute to atherosclerosis progression, and its inhibition could stabilize plaques, but it does not reduce plaque size.
Not reported in abstract.