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Myostatin's flex on the reproductive hormone axis.
ACE-031 (ACVR2B-Fc) · Science (New York, N.Y.) · 2025Top journal
Not reported in abstract.
Research library
Every indexed study on every peptide in the database, with a machine summary and the numbers that matter pulled out. Filter on the left; the register updates as you go.
2255studies indexed1010with human data129registered trials1946carry a numeric findingLibrarian added 23 studies today
Showing 8 studiesSortNewest indexed ▾
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Apitegromab for lean mass preservation during tirzepatide-induced weight loss: a randomized, double-blind, placebo-controlled phase 2 trial.
ACE-031 (ACVR2B-Fc) · Nature medicine · 2026Top journal
Not reported in abstract.
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Antibodies to watch in 2026.
ACE-031 (ACVR2B-Fc) · mAbs · 2026 · Review
The antibody therapeutics pipeline is expanding, with numerous products nearing regulatory review and a typical development period of around 6 years.
Development and approval period typically ~6 years.
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Multi-omics dissection of metabolic hijacking: Infectious bronchitis virus orchestrates lipid-centric replication through PPAR-TGF-β crosstalk.
ACE-031 (ACVR2B-Fc) · Virulence · 2026 · Animal study · Preclinical
IBV manipulates host lipid metabolism to support its replication, highlighting potential metabolic targets for antiviral strategies.
2.55-fold increase in phosphatidylserine (PS(22:0/22:6))
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Cardiometabolic index (CMI) and sarcopenia as predictors of all-cause and cardiovascular mortality in chronic kidney disease: a NHANES-based cohort study.
ACE-031 (ACVR2B-Fc) · Renal failure · 2026 · Observational · n=1886
Elevated CMI and sarcopenia are associated with increased mortality risk in CKD patients, particularly when both are present.
HR = 4.03 for cardiovascular mortality in highest CMI quartile, 95% CI: 1.52-10.70
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Gel Electrophoretic Detection of Black Market ACE-031.
ACE-031 (ACVR2B-Fc) · Drug testing and analysis · 2025 · Observational
This study found that 12 out of 14 black market ACE-031 products contained an ACVR2B-immunoreactive protein, but the detection in rats may not reflect human metabolism.
In rat serum, BM ACE-031 was detectable up to 48 h post administration.
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ACE-031, a soluble activin type IIB receptor, increases muscle mass and strength in the common marmoset (Callithrix jacchus).
ACE-031 (ACVR2B-Fc) · PloS one · 2026 · RCT · Preclinical
ACE-031 appears to increase muscle mass and strength in common marmosets, but the relevance of these findings to human treatment is not established.
Not reported in abstract.
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Gel Electrophoretic Detection of Black Market ACE-031.
ACE-031 (ACVR2B-Fc) · PubMed · 2025 · Observational · n=20
The study found that 12 out of 14 black market ACE-031 products contained a different protein than expected, and in rats, it was detectable for up to 48 hours after administration.
10 mg/kg body weight administered in rats.
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