Peptides DB
Research-centric peptide and protocol reference hub
Study 1 of 35PE 22-28 literaturePubMed · Observational2026

Haemodynamic assessment of the superficial inferior epigastric artery to demonstrate the vascularisation of a new lower transverse abdominal flap.

The study identifies areas I and II of the SIEAs as having satisfactory perfusion for surgical use, while areas III and IV are not recommended due to poor perfusion.

Read at PubMedAdd to compare

Where it sits

this study against the rest of the pe 22-28 corpus
2
Preclinical
31
Observational · this one
0
Open-label
1
Randomised
1
Reviews

Summary and findings

This study evaluated the haemodynamics of the superficial inferior epigastric arteries (SIEAs) in surgical specimens from abdominoplasties to identify optimal regions for a lower transverse abdominal flap. A total of 78 specimens were analyzed, with findings indicating significant differences in SIEA diameters between two groups: post-bariatric surgery and those without prior surgery. Perfusion was satisfactory in areas I and II, while areas III and IV showed unsatisfactory perfusion.

How much of this paper we could read: full text read (0.80). We had a clear abstract, so the summary below closely tracks the paper. What this means →
100% contrast filling in areas I and II.2026

Abstract

The authors’ words, as PubMed supplied them

Haemodynamics examines the mechanics of blood circulation to define anatomy, support diagnosis, and guide treatment of tissue and organ alterations. The superficial inferior epigastric arteries (SIEAs) were studied in surgical specimens discarded from abdominoplasties to evaluate the most perfused regions for creating the lower transverse abdominal flap. In this observational, descriptive, and analytical study (2021-2024), SIEAs from 78 abdominoplasty specimens were catheterised, divided into four regions, and subjected to haemodynamic analysis. Two groups were studied: G1 (post-bariatric surgery) and G2 (without prior surgery). Numerical variables were summarised using measures of central tendency and dispersion. Associations between categorical variables were tested with Fisher's exact test. The Shapiro-Wilk test assessed the normality of quantitative variables. Comparisons between two independent groups used Student's t-test for normally distributed data and the Mann-Whitney U test for non-normal distributions. For paired groups, the paired Student's t-test was applied for normal data, and the Wilcoxon and Spearman tests for non-normal data. Women comprised 71 participants (91.0%). G1 included 22 (28.2%), and G2 included 56 (71.8%). Statistically significant differences were observed between G1 and G2 in SIEA diameters. Haemodynamic analysis showed satisfactory perfusion in areas I and II (100% contrast filling of the vascular territory), whereas areas III (33.3%) and IV (6.7%) demonstrated unsatisfactory perfusion. This study demonstrated the anatomy and flow of the SIEAs and identified the safest regions of the flap for surgical use. Areas I and II were safe, whereas areas III and IV were not.

Background

The paper addresses the vascularization of the superficial inferior epigastric artery, which is crucial for the viability of lower transverse abdominal flaps in surgical procedures. Prior knowledge indicates that adequate blood supply is essential for flap survival, but specific assessments of this artery's haemodynamics in relation to new flap designs are limited. This study aims to fill that gap by providing empirical data on the artery's function.

Methods

Not reported in abstract.

Results

Not reported in abstract.

Interpretation

Not reported in abstract.

Key findings

  • Not reported in abstract.

Limitations

  • Not reported in abstract.

Elsewhere in the PE 22-28 corpus

CShortened Spadin Analogs Display Better TREK-1 Inhibition, <i>In Vivo</i> Stability and Antidepressant Activity.Frontiers in pharmacology · 2017 · IC50 of PE 22-28 was 0.12 nM vs. 40-60 nM for spadin.AnimalCN-terminal fusion length: The key to reliable and context-preserving regulatory sequence characterization.Synthetic and systems biotechnology · 2026 · mean R² > 0.75In vitroCEnhancing pectin degradation and improving nutritional accessibility in potato pulp through co-fermentation: From molecular structure to nutrient release.Food microbiology · 2026 · Pectin degradation reached 29.26 ± 0.41% under optimized conditions.AnimalCDiscovery of an Isothiazolinone-Containing Antitubercular Natural Product Levesquamide.The Journal of organic chemistry · 2020 · MIC of 9.65 μM against Mycobacterium tuberculosis H37Rv in microplate alamarBlue assay.In vitroCLymph node-targeted Nanovaccine Reshapes the Tumor Microenvironment to Suppress PDAC Progression and Metastasisbiorxiv-preprint · 2026 · Not reported in abstract.AnimalCTGF-β, but not IL-4, polarized macrophages induce fibrotic responses in lung fibroblastsbiorxiv-preprint · 2026 · Not reported in abstract.In vitro