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Study 3 of 9GHRP-6 literatureeuropepmc · Observational2026

Healthcare inequity in mpox testing intention: A socioeconomic status-stratified path analysis of medical discrimination and distrust among men who have sex with men in China.

Over half of the participants reported high intention to get tested for mpox, but the influence of medical discrimination and distrust varies significantly between high and low socioeconomic status groups.

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Preclinical
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Observational · this one
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Summary and findings

This study examined the impact of medical discrimination and distrust on mpox testing intention among men who have sex with men (MSM) in China, stratified by socioeconomic status (SES). A total of 2403 participants were surveyed from November 2023 to March 2024. Findings indicated that 50.7% reported high testing intention, with varying effects of discrimination and distrust across SES groups.

How much of this paper we could read: full text read (0.80). We had a clear abstract, so the summary below closely tracks the paper. What this means →
50.7% of 2403 participants reported high testing intention.2026

Abstract

The authors’ words, as europepmc supplied them

<h4>Background</h4>Global mpox outbreaks have exposed healthcare inequities in testing accessibility. Socioeconomic disparities and medical discrimination and distrust influence testing service utilization among vulnerable populations. We examined how medical discrimination and distrust affect testing intention across socioeconomic strata among men who have sex with men (MSM) in China.<h4>Methods</h4>We conducted a nationwide cross-sectional study across six regions of China (November 2023 to March 2024). MSM aged ≥ 18 years who reported male sexual partners within previous six months were recruited through local Centers for Disease Control and Prevention and community-based organizations. Participants completed anonymous questionnaires measuring medical discrimination and distrust (DS), structural determinants, behavioral factors, psychosocial factors, and mpox testing intention<i>.</i> Path analysis was used to examine the effects of medical discrimination and distrust on testing intention, stratified by socioeconomic status (SES).<h4>Results</h4>50.7% of 2403 participants reported high testing intention. Path analysis revealed that medical discrimination and distrust were associated with testing intention through distinct mechanisms across SES groups. For high-SES participants, positive indirect associations were found between medical discrimination and distrust and testing intention (<i>β</i> = 0.061, <i>P</i> < 0.001) mediated by voluntary HIV counseling and testing services, social support and depression. For low-SES participants, medical discrimination and distrust demonstrated a negative direct effect (<i>β</i> = -0.218, <i>P</i> < 0.001) and indirect effects through social support, depression, and mpox prevention-related self-efficacy (<i>β</i> = -0.028, <i>P</i> < 0.001)<i>.</i> Social support emerged as a crucial mediator among low-SES groups, while depression served as the crucial mediator among high-SES groups.<h4>Conclusions</h4>Healthcare inequities manifest through socioeconomically patterned pathways affecting mpox testing intention. Our findings suggest differentiated intervention strategies: integrating services with existing healthcare infrastructure for high-SES populations while strengthening community-based support for low-SES groups. These insights inform efforts to address healthcare disparities in infectious disease responses, particularly in resource-limited settings.

Background

Not reported in abstract.

Methods

Not reported in abstract.

Results

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Interpretation

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Key findings

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Limitations

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