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Study 10 of 19Thymulin (Facteur Thymique Serique) literatureToxicology reports · Observational2026

Per- and polyfluoroalkyl substances in commercially important marine species of fish and shellfish from Alaska and implications for human exposure.

PFAS levels in commercially important seafood from Alaska are generally low, with the highest detected concentration being 0.809 ng/g wet weight.

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this study against the rest of the thymulin (facteur thymique serique) corpus
5
Preclinical
9
Observational · this one
1
Open-label
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Randomised
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Reviews

Summary and findings

This study analyzed muscle tissue from various fish and shellfish species harvested in Alaska for 40 per- and polyfluoroalkyl substances (PFAS) analytes. Ten analytes were detected above the method detection limit, with concentrations ranging from below detection to 0.809 ng/g wet weight. The findings indicate that overall PFAS concentrations were low or non-detect.

How much of this paper we could read: full text read (0.70). We had a clear abstract, so the summary below closely tracks the paper. What this means →
0.809 ng/g wet weight.2026

Abstract

The authors’ words, as Toxicology reports supplied them

Per- and polyfluoroalkyl substances (PFAS) are persistent environmental synthetic contaminants associated with some adverse health effects under certain exposure conditions. Dietary sources, particularly seafood, have been identified as a potentially significant contributor to PFAS body burden. Muscle tissue from several species of fish and shellfish harvested in Alaska were analyzed for 40 PFAS analytes. Ten analytes were detected above the method detection limit (MDL) with PFTrDA and PFUnA being the most frequently detected. Concentrations of all analytes ranged from below the detection limit to 0.809 ng/g wet weight with most being below the limit of quantification (LOQ). Overall, PFAS concentrations were low or non-detect, consistent with other market basket studies of seafood. Although no national PFAS-specific fish consumption thresholds are currently established, ongoing surveillance of PFAS in commercially and recreationally harvested seafood provides critical exposure data to inform risk assessment and regulatory decision-making.

Background

This paper addresses the presence of per- and polyfluoroalkyl substances (PFAS) in commercially important marine species of fish and shellfish from Alaska. PFAS are known persistent environmental contaminants that may pose health risks under certain exposure conditions. Understanding the levels of PFAS in seafood is crucial for assessing potential human exposure and informing regulatory decisions.

Methods

Muscle tissue from several species of fish and shellfish harvested in Alaska was analyzed for 40 PFAS analytes. The study focused on detecting the presence of these substances and quantifying their concentrations. Specific details regarding the sample size, duration, and analytical methods were not reported in the abstract.

Results

Ten analytes were detected above the method detection limit, with concentrations ranging from below the detection limit to 0.809 ng/g wet weight. Most analytes were reported to be below the limit of quantification. The findings indicate that overall PFAS concentrations in the tested seafood were low or non-detect.

Interpretation

The results align with other market basket studies of seafood, suggesting that PFAS concentrations in commercially harvested seafood may be low. While the detection of PFAS is significant, the concentrations reported may not be clinically meaningful given the low levels observed. Limitations include the lack of established national PFAS-specific fish consumption thresholds and the need for ongoing surveillance to better inform risk assessments.

Key findings

  • Concentrations of all analytes ranged from below the detection limit to 0.809 ng/g wet weight.
  • Ten analytes were detected above the method detection limit.
  • Most analytes were below the limit of quantification.

Limitations

  • Not reported in abstract.
  • No national PFAS-specific fish consumption thresholds established.
  • Ongoing surveillance needed for comprehensive risk assessment.

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