Study 8 of 8ACE-031 (ACVR2B-Fc) literatureScience (New York, N.Y.)Top journal2025
Myostatin's flex on the reproductive hormone axis.
Not reported in abstract.
Where it sits
this study against the rest of the ace-031 (acvr2b-fc) corpus2
Preclinical · this one
3
Observational
1
Open-label
1
Randomised
1
Reviews
Summary and findings
Not reported in abstract.
How much of this paper we could read: title only (0.10). The feed gave us little more than the title, so our summary is thin. This says nothing about the study's quality — read the source. What this means →
2025
Abstract
The authors’ words, as Science (New York, N.Y.) supplied them
A muscle hormone controls the mammalian reproductive system.
Background
Not reported in abstract.
Methods
Not reported in abstract.
Results
Not reported in abstract.
Interpretation
Not reported in abstract.
Limitations
Not reported in abstract.
Elsewhere in the ACE-031 (ACVR2B-Fc) corpus
BApitegromab for lean mass preservation during tirzepatide-induced weight loss: a randomized, double-blind, placebo-controlled phase 2 trial.Nature medicine · 2026HumanDAntibodies to watch in 2026.mAbs · 2026 · Development and approval period typically ~6 years.reviewCMulti-omics dissection of metabolic hijacking: Infectious bronchitis virus orchestrates lipid-centric replication through PPAR-TGF-β crosstalk.Virulence · 2026 · 2.55-fold increase in phosphatidylserine (PS(22:0/22:6))AnimalBCardiometabolic index (CMI) and sarcopenia as predictors of all-cause and cardiovascular mortality in chronic kidney disease: a NHANES-based cohort study.Renal failure · 2026 · n=1886 · HR = 4.03 for cardiovascular mortality in highest CMI quartile, 95% CI: 1.52-10.70HumanCGel Electrophoretic Detection of Black Market ACE-031.Drug testing and analysis · 2025 · In rat serum, BM ACE-031 was detectable up to 48 h post administration.AnimalCACE-031, a soluble activin type IIB receptor, increases muscle mass and strength in the common marmoset (Callithrix jacchus).PloS one · 2026 · Not reported in abstract.Animal