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Study 12 of 19Lixisenatide literatureSSM. Mental health · Observational2026

Suicidal thoughts and behaviours in Cape Town: A cross-sectional study of prevalence and social, contextual, and clinical correlates.

The prevalence of suicidal thoughts and behaviors is notably high in peri-urban Cape Town, with strong associations to mental health issues and social stressors.

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Where it sits

this study against the rest of the lixisenatide corpus
1
Preclinical
14
Observational · this one
0
Open-label
2
Randomised
2
Reviews

Summary and findings

This study examined the prevalence of suicidal thoughts and behaviors (STBs) in two communities in Cape Town, focusing on socioeconomic, psychosocial, and clinical correlates. A total of 613 adults aged ≥18 years were enrolled, with 65.4% living with HIV. The study reported a 14.0% prevalence of past 30-day suicidal ideation and 22.2% for lifetime suicide attempts.

How much of this paper we could read: full text read (0.80). We had a clear abstract, so the summary below closely tracks the paper. What this means →
14.0% prevalence of past 30-day suicidal ideation, n=613.2026

Abstract

The authors’ words, as SSM. Mental health supplied them

<h4>Background</h4>Suicidal thoughts and behaviours (STBs) are traditionally attributed to mental disorders; however, increasing evidence indicates that social determinants contribute to suicide risk. We examined STBs and their socioeconomic, psychosocial and clinical correlates in two communities in Cape Town.<h4>Methods</h4>We conducted psychiatric diagnostic interviews (MINI) at three public-sector facilities (2023-2024). Adults aged ≥18 years, with and without HIV, were recruited in a 2:1 ratio. We examined associations between suicidal ideation and sociodemographic factors, violence exposure, perceived stress, mental disorders, and HIV, reporting average marginal effects (AME) as percentage-point differences in predicted probability.<h4>Results</h4>We enrolled 613 participants (63.9% female; 65.4% living with HIV; median age 39). The prevalence of past 30-day suicidal ideation was 14.0%, while 22.2% reported a lifetime suicide attempt. Suicidal ideation was more likely among females (8.52 percentage points, 95% CI 3.08 -13.96), those reporting violence in the community (7.52, 0.87 -14.17) or in the family (14.09, 4.56 -23.62), those with moderate (7.76, 2.76 -12.77) or high perceived stress (33.58, 20.67 -46.50), and those with depression (27.13, 14.67 -39.58), post-traumatic stress disorder (27.98, 12.12 -43.84), or alcohol use disorder (8.34, 1.53 -15.15). Associations with high perceived stress and community violence persisted after adjustment for mental disorders. HIV status and other sociodemographic factors showed no evidence of association.<h4>Conclusion</h4>STB prevalence was high in peri-urban communities in Cape Town and strongly associated with mental disorders, violence exposure, and perceived stress. These findings underscore the role of structural and psychosocial stressors in shaping suicide risk in low-income communities.

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