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Study 7 of 11Selank literatureEmerging adulthood (Print) · Observational2023

The Dysregulation Profile and Substance Use: Investigating Their Co-Variation From Adolescence to Emerging Adulthood.

Dysregulation appears to increase during adolescence and decrease in emerging adulthood, with higher substance use linked to greater dysregulation.

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Where it sits

this study against the rest of the selank corpus
3
Preclinical
7
Observational · this one
0
Open-label
1
Randomised
0
Reviews

Summary and findings

This study examined the relationship between dysregulation and substance use in 662 Canadian youth over a 10-year period. Dysregulation increased during adolescence and declined in emerging adulthood. Higher average substance use was associated with higher overall dysregulation.

How much of this paper we could read: full text read (0.80). We had a clear abstract, so the summary below closely tracks the paper. What this means →
Not reported in abstract.n=6622023

Abstract

The authors’ words, as Emerging adulthood (Print) supplied them

Children and youth with the Dysregulation Profile (DP) experience marked difficulties regulating cognition, affect, and behavior. Although these impairments are known to have lasting effects into adulthood, less is understood about how dysregulation changes during the transition from adolescence to emerging adulthood. Dysregulation has also been linked to increased risk for substance use disorder, yet its relationship with substance use during the adolescence-to-emerging-adulthood transition remains unclear. This study examined how dysregulation covaries with substance use from adolescence to emerging adulthood in 662 Canadian youth (Mage = 15.52) followed over 10 years. Multilevel modeling showed that dysregulation increased during adolescence and declined in emerging adulthood. Both between- and within-person substance use predicted dysregulation: higher average substance use was associated with higher overall dysregulation, and above-average substance use corresponded to higher dysregulation at the same time point. These findings clarify developmental changes in dysregulation and highlight its close association with substance use.

Background

This paper addresses the developmental trajectory of dysregulation and its relationship with substance use during the transition from adolescence to emerging adulthood. Previous research has established that dysregulation can lead to difficulties in emotional and behavioral regulation, but less is known about how this dysregulation evolves over time. Understanding these dynamics is important for identifying potential interventions for youth at risk of substance use disorders.

Methods

The study utilized a longitudinal design, following 662 Canadian youth over 10 years. The primary outcome measures included self-reported levels of dysregulation and substance use. Multilevel modeling was employed to analyze the data.

Results

Dysregulation increased during adolescence and declined in emerging adulthood. Higher average substance use was associated with higher overall dysregulation, and above-average substance use corresponded to higher dysregulation at the same time point.

Interpretation

The findings align with existing literature that suggests a relationship between dysregulation and substance use. However, the effect sizes are not quantified in the abstract, making it difficult to assess clinical significance. The study's reliance on self-reported data and its correlational nature limit the ability to draw causal conclusions.

Key findings

  • n=662 Canadian youth, Mage = 15.52, followed over 10 years.
  • Dysregulation increased during adolescence and declined in emerging adulthood.
  • Higher average substance use was associated with higher overall dysregulation.
  • Above-average substance use corresponded to higher dysregulation at the same time point.

Limitations

  • self-reported measures may introduce bias
  • correlational design does not imply causation
  • longitudinal study may have attrition bias

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