Peptides DB
Research-centric peptide and protocol reference hub
Study 8 of 135-amino-1MQ literatureEuropean journal of psychotraumatology · RCT · Phase 22026

Emotion regulation skills training as an adjunctive treatment to narrative exposure therapy for posttraumatic stress disorder (PTSD) in refugees: a pilot randomized controlled trial.

Both STAIR-R combined with NET and SPS plus NET reduced PTSD symptoms in refugees, but no significant differences were found between the two treatments. Tailored approaches may be beneficial for those with high insecurity.

Read at European journal of psychotraumatologyAdd to compare

Where it sits

this study against the rest of the 5-amino-1mq corpus
1
Preclinical
11
Observational
0
Open-label
1
Randomised · this one
0
Reviews

Summary and findings

This study evaluated the efficacy of Skills Training in Affective and Interpersonal Regulation for Refugees (STAIR-R) combined with Narrative Exposure Therapy (NET) versus Supportive Problem-Solving (SPS) plus NET in refugees with PTSD. Seventy-one participants were randomly assigned to one of the two treatment groups, with assessments at baseline, post-treatment, and 3-month follow-up. Both groups showed improvements in PTSD symptoms, but no significant differences were found between the groups overall.

How much of this paper we could read: full text read (0.80). We had a clear abstract, so the summary below closely tracks the paper. What this means →
g=-1.54 for SPS+NET, p<0.001 at 3-month follow-up for clinician-assessed PTSD symptoms.n=71Phase 22026

Abstract

The authors’ words, as European journal of psychotraumatology supplied them

<b>Background:</b> Responses to evidence-based interventions for posttraumatic stress disorder (PTSD) in refugees vary considerably. Emotion regulation difficulties are associated with greater PTSD severity in refugees and thus represent a potential treatment target.<b>Objective:</b> This study aimed to test the efficacy of Skills Training in Affective and Interpersonal Regulation for Refugees (STAIR-R) and Narrative Exposure Therapy (NET) or Supportive Problem-Solving (SPS) and NET. An exploratory aim was to examine relative efficacy in refugees with high and low levels of visa and family insecurity.<b>Methods:</b> Seventy-one participants were randomly assigned to STAIR-R (6 sessions) + NET (7 sessions) or SPS (6 sessions) +NET (7 sessions). Assessments occurred at baseline, post-treatment, and 3-month follow-up, with additional self-report at mid-treatment. The primary outcome was clinician-assessed PTSD symptom severity (CAPS-5) and secondary outcomes included self-reported PTSD symptoms, depression symptoms, emotion regulation difficulties, difficulties in relationships and environmental quality of life.<b>Results:</b> Intent-to-treat linear mixed models showed no significant between-group differences at mid-treatment, post-treatment, or follow-up. Both groups demonstrated significant improvements at 3-month follow-up in clinician-assessed (STAIR-R + NET, <i>g = -1.41</i>; SPS + NET, <i>g</i> = -1.54, <i>p</i> < .001) and self-reported (STAIR-R + NET, <i>g</i> = -0.49; SPS + NET, <i>g</i> = -0.44, <i>p</i> = .006) PTSD symptoms. Moderatorg analyses revealed that those with high insecurity (<i>n</i> = 16) obtained greater benefits in STAIR-R + NET from pre-treatment to follow-up on self-reported PTSD (<i>g</i> = 1.35), depression (<i>g</i> = 1.11), emotion regulation difficulties (<i>g</i> = 1.24), relationship difficulties (<i>g</i> = 1.12) and quality of life (<i>g</i> = -1.05).<b>Conclusions:</b> While there were no overall between group-differences, refugees in both conditions showed reduced PTSD symptoms. There is preliminary evidence that those with high insecurity showed a better response to STAIR-R + NET than SPS + NET across several clinical outcomes, although the small sample size necessitates replication of these. These findings highlight the potential importance of tailored intervention approaches for refugees living in different environmental circumstances.

Background

This paper addresses the variability in responses to evidence-based interventions for PTSD in refugees, highlighting the association between emotion regulation difficulties and PTSD severity. Prior research has indicated that tailored interventions may improve treatment outcomes for this population. The study's exploration of the efficacy of STAIR-R combined with NET versus SPS plus NET aims to contribute to understanding effective treatment strategies for refugees.

Methods

The study utilized a pilot randomized controlled trial design with 71 participants assigned to either STAIR-R (6 sessions) + NET (7 sessions) or SPS (6 sessions) + NET (7 sessions). Assessments were conducted at baseline, post-treatment, and at a 3-month follow-up, with additional self-report measures at mid-treatment. The primary outcome was clinician-assessed PTSD symptom severity measured by CAPS-5, while secondary outcomes included self-reported PTSD symptoms, depression symptoms, emotion regulation difficulties, relationship difficulties, and environmental quality of life.

Results

The primary endpoint showed no significant between-group differences at mid-treatment, post-treatment, or follow-up. Both treatment groups demonstrated significant improvements in clinician-assessed PTSD symptoms at 3-month follow-up (STAIR-R + NET, g=-1.41; SPS + NET, g=-1.54, p<0.001) and self-reported PTSD symptoms (STAIR-R + NET, g=-0.49; SPS + NET, g=-0.44, p=0.006). Moderator analyses indicated that participants with high insecurity (n=16) experienced greater benefits in STAIR-R + NET across multiple clinical outcomes.

Interpretation

The findings suggest that while both treatment approaches led to improvements in PTSD symptoms, the lack of significant between-group differences indicates that neither intervention was superior overall. The effect sizes observed, particularly in the high insecurity subgroup, may warrant further investigation, although the small sample size raises concerns about the robustness of these results. This study highlights the need for tailored interventions based on individual circumstances in refugee populations.

Key findings

  • g=-1.41 for STAIR-R+NET and g=-1.54 for SPS+NET, p<0.001 at 3-month follow-up for clinician-assessed PTSD symptoms.
  • g=-0.49 for STAIR-R+NET and g=-0.44 for SPS+NET, p=0.006 at 3-month follow-up for self-reported PTSD symptoms.
  • Moderators showed that those with high insecurity (n=16) had a g=1.35 improvement in self-reported PTSD from pre-treatment to follow-up.
  • g=1.11 for depression, g=1.24 for emotion regulation difficulties, g=1.12 for relationship difficulties, and g=-1.05 for quality of life in high insecurity group.
  • No significant between-group differences at mid-treatment, post-treatment, or follow-up.

Limitations

  • small sample size n=71
  • no significant between-group differences
  • high insecurity subgroup analysis limited to n=16
  • short follow-up period of 3 months

Elsewhere in the 5-amino-1MQ corpus

BDissecting the effect of long-term exposure to air pollution on risk of dementia in UK Biobank.Environmental health : a global access science source · 2025 · HR=1.06 (1.02-1.11) per 9.86 µg/m³ interquartile range of NO₂ exposure.HumanCIntegrative metabolomic and transcriptomic analysis reveals stage-specific shifts in hepatic lipid metabolism of broiler chickens.Animal biotechnology · 2026 · 1121 metabolites identified.AnimalBThe association between serum indoxyl sulfate and radial-cephalic arteriovenous fistulas dysfunction in ESKD patients: a prospective study.Renal failure · 2026 · n=113 · AUC = 0.87 for the 1-year patency nomogram.HumanBAccelerated mutator phenotype in a clinical &lt;i&gt;Aspergillus fumigatus&lt;/i&gt; isolate contributes to adaptive evolution.Emerging microbes & infections · 2026 · Mutation frequency was approximately 15-times higher than other A. fumigatus strains.HumanBInternet Cognitive Therapy for Prolonged Grief Disorder (iCT-PG): a developmental case series.European journal of psychotraumatology · 2026 · n=8 · 87.5% (7/8) demonstrated reliable improvement in PGD symptoms on the Reliable Change Index at post-treatment.HumanBThe impact of nonpharmaceutical interventions (NPIs) on rabies post-exposure prophylaxis: A comparative study in Wuhan, 2022 vs. 2023.Human vaccines & immunotherapeutics · 2026 · 33.17% category III exposures in 2022 vs 36.01% in 2023.Human