Study 18 of 47NAD+ (Nicotinamide Adenine Dinucleotide) literatureScience (New York, N.Y.)Top journal2026
The placental metabolic clock.
NAD+ depletion appears to trigger a countdown to birth in mice, but the implications for human pregnancy remain unclear.
Where it sits
this study against the rest of the nad+ (nicotinamide adenine dinucleotide) corpus17
Preclinical · this one
23
Observational
1
Open-label
1
Randomised
5
Reviews
Summary and findings
This study investigates the role of NAD+ depletion in the timing of birth in mice. The findings suggest that NAD+ levels may influence the metabolic processes leading to parturition. No therapeutic claims are made regarding the implications of these findings.
How much of this paper we could read: title only (0.30). The feed gave us little more than the title, so our summary is thin. This says nothing about the study's quality — read the source. What this means →
2026
Abstract
The authors’ words, as Science (New York, N.Y.) supplied them
NAD+ depletion triggers a countdown to birth in mice.
Background
Not reported in abstract.
Methods
Not reported in abstract.
Results
Not reported in abstract.
Interpretation
Not reported in abstract.
Key findings
- Not reported in abstract.
- Not reported in abstract.
- Not reported in abstract.
Limitations
- Not reported in abstract.
- Not reported in abstract.
Elsewhere in the NAD+ (Nicotinamide Adenine Dinucleotide) corpus
CBioactive vitamin E-NAD<sup>+</sup> conjugate nanoparticles for osteoarthritis management via simultaneous suppression of inflammation and oxidative stress.Biomaterials · 2026 · Not reported in abstract.AnimalBNAD metabolism mediates a sex-specific protection against early life infectionsbiorxiv-preprint · 2026 · Higher birth NAD levels in females were associated with reduced infection burdens during the first 3 years of life.HumanBControl-referenced bacterial bioluminescence reveals a two-axis salivary response phenotype in benign and malignant breast disease.Talanta · 2026 · n=200 · Not reported in abstract.HumanBGenetic modulation of NAD(P)H homeostasis reveals distinct redox-coupled metabolic vulnerabilities.Nature metabolism · 2026 · Not reported in abstract.HumanDA context-dependent framework for targeting NAD metabolism in cancer.Cell metabolism · 2026reviewBPart 1 of a 2-part, open-label clinical trial evaluating repeated nicotinamide riboside parenteral administration: 3 consecutive days of intramuscular and subcutaneous injectionsbiorxiv-preprint · 2026 · 9.97% average daily increase in NAD+ for 100 mg IM.Human