Study 19 of 37NAD+ (Nicotinamide Adenine Dinucleotide) literatureScience (New York, N.Y.)Top journal2026
The placental metabolic clock.
NAD+ depletion appears to trigger a countdown to birth in mice, but the implications for human pregnancy remain unclear.
Where it sits
this study against the rest of the nad+ (nicotinamide adenine dinucleotide) corpus17
Preclinical · this one
15
Observational
0
Open-label
1
Randomised
4
Reviews
Summary and findings
This study investigates the role of NAD+ depletion in the timing of birth in mice. The findings suggest that NAD+ levels may influence the metabolic processes leading to parturition. No therapeutic claims are made regarding the implications of these findings.
How much of this paper we could read: title only (0.30). The feed gave us little more than the title, so our summary is thin. This says nothing about the study's quality — read the source. What this means →
2026
Abstract
The authors’ words, as Science (New York, N.Y.) supplied them
NAD<sup>+</sup> depletion triggers a countdown to birth in mice.
Background
Not reported in abstract.
Methods
Not reported in abstract.
Results
Not reported in abstract.
Interpretation
Not reported in abstract.
Key findings
- Not reported in abstract.
- Not reported in abstract.
- Not reported in abstract.
Limitations
- Not reported in abstract.
- Not reported in abstract.
Elsewhere in the NAD+ (Nicotinamide Adenine Dinucleotide) corpus
CThe mitochondrial deacetylase SIRT3 is nonessential for cyclophilin D-dependent procoagulant platelet formation in mice.Platelets · 2026 · Not reported in abstract.AnimalDA comprehensive review of small molecule drugs approved by the FDA in 2025: advance and prospect.Journal of enzyme inhibition and medicinal chemistry · 2026 · 31 of 46 FDA-approved drugs in 2025 were small molecule drugs.reviewCNicotinamide-derived tumor-targeting carbon dots for Cancer Photothermal therapy.Journal of colloid and interface science · 2026 · Binding energy of NAM-CDs to Ki67 was -7.7 kcal/mol.AnimalCMitochondrial-targeted nano-enhancer driving a self-amplifying NAD<sup>+</sup> feedback loop to reprogram MSC spheroids metabolism for accelerated bone regeneration.Biomaterials · 2026In vitroDPyridoxal photoenzymes for asymmetric radical-radical cross-couplings.Nature · 2026—CPhage anti-defense genes targeting NAD<sup>+</sup> metabolism and DNA replication are associated with a broad host range against <i>Klebsiella pneumoniae</i>.Virulence · 2026 · Not reported in abstract.Animal