Peptides DB

Research-centric peptide and protocol reference hub

NAD+

Research-centric overview

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### Summary NAD+ (Nicotinamide adenine dinucleotide) is a crucial coenzyme involved in various metabolic processes, including energy production and cellular repair mechanisms. Recent research highlights its potential roles in protecting against oxidative stress and enhancing therapeutic efficacy in certain cancer treatments.

Community effect votes, structured logs, and side-effect summaries.

Effect profile (overview)

Aggregate AI baseline blended with community voting. Hover to inspect effect strengths per category.

Effect profile (AI + community): Healing & recovery 3.0/5 · Muscle & body comp 2.0/5 · Metabolic & appetite 4.0/5 · Neuro & mood 3.0/5 · Sleep & circadian 1.0/5 · Inflammation & immune 3.0/5 · Skin & aesthetics 2.0/5Healing 3.0Muscle 2.0Metabolic 4.0Neuro 3.0Sleep 1.0Inflammation 3.0Skin 2.0

Effect scores blend an AI baseline with community votes. Open the full chart to see sliders and vote on each category.

Research log summary heatmap

Compact view of how logs describe shifts in pain, sleep, and performance (−5 to +5). Treat this as qualitative, anonymous signal only.

No community research logs yet. When structured logs are added, this panel will summarize typical shifts in pain, sleep, and performance.

Anonymous side-effect patterns

Rough heatmap of anonymous side-effect and positive-signal tags — a "most-mentioned" snapshot, not safety or efficacy advice.

No anonymous side-effect reports yet. When reports are submitted, this panel will show a simple heatmap of tags like "nausea", "flushing", "improved healing", and more.

Research footprint

Last analyzed Jun 2, 2026
11
Studies indexed
0
Human
2
Animal
11
AI analyzed
Evidence mix0% human · 18% animal · 0% cellular · 0% review
Highest phase: PreclinicalYears covered: 2026
Librarian pulse — latest actionsFull changelog ↓
  • Jun 2, 5:00 PMRe-scoredScored effects for NAD+
  • Jun 1, 6:00 AMRefreshedRefreshed content for NAD+
  • May 31, 6:00 AMRefreshedRefreshed content for NAD+

Research & intelligence feed

Studies, clinical trials, community discussions, and news.

Observational and Transversal Study of Patients Treated in "Real Life"Conditions With Adaptive Servo-VentilationClinical TrialClinicalTrials.govPublished Mar 13, 2015Added May 27, 2026

This study observed patients treated with Adaptive Servo-Ventilation (ASV) in real-life conditions. The specific outcomes measured and the patient demographics were not detailed in the abstract. The study aimed to assess the effectiveness of ASV in a clinical setting.

Phase: NAStatus: COMPLETED
Suboxone and Methadone for HIV Risk Reduction in Subutex InjectorsClinical TrialClinicalTrials.govPublished Jun 1, 2010Added May 27, 2026

This study evaluated the effects of Suboxone and Methadone on HIV risk reduction among individuals who inject Subutex. The specific doses and outcomes were not detailed in the abstract. The findings are relevant for understanding the potential role of these medications in harm reduction strategies.

Phase: PHASE3Status: COMPLETED
Double-blind Placebo Controlled Study to Evaluate the Effect of NAD+ Boosting With Nicotinamide Riboside on Immunometabolism and Immunity in Systemic Lupus ErythematosusClinical TrialClinicalTrials.govPublished Mar 13, 2024Added May 27, 2026

This study evaluated the effect of NAD+ boosting with nicotinamide riboside on immunometabolism and immunity in patients with systemic lupus erythematosus. The specific dose and outcomes measured were not detailed in the abstract. The study design was a double-blind placebo-controlled trial.

Phase: PHASE1, PHASE2Status: RECRUITING
Colorectal Cancer Screening Detects Tumors at Earlier Stages Improving Clinical OutcomesClinical TrialClinicalTrials.govPublished Mar 1, 2013Added May 27, 2026

Not reported in abstract.

Status: COMPLETED
Using Structured Video Chat to Improve Relationships Between Young Children and Remote GrandparentsClinical TrialClinicalTrials.govPublished Nov 1, 2022Added May 27, 2026

Not reported in abstract.

Phase: NAStatus: ACTIVE_NOT_RECRUITING
A Phase 1 Open-label Study of KPT-9274 in Patients With Relapsed and Refractory Acute Myeloid LeukemiaClinical TrialClinicalTrials.govPublished Aug 27, 2021Added Apr 16, 2026

This study evaluated KPT-9274 in patients with relapsed and refractory acute myeloid leukemia (AML). The specific dose and outcomes were not detailed in the abstract. The study's findings are relevant for understanding the potential effects of KPT-9274 in this patient population.

Phase: PHASE1Status: COMPLETED
A Randomized, Double-blind, Placebo-controlled, Parallel-group, Phase 3, Multicenter Trial Investigating the Efficacy and Safety of C21 as add-on to Standard of Care in Adult Subjects With COVID-19Clinical TrialClinicalTrials.govPublished Sep 16, 2021Added Apr 16, 2026

This study investigated the efficacy and safety of C21 as an add-on to standard care in adult subjects with COVID-19. The trial was randomized, double-blind, and placebo-controlled. Not reported in abstract.

Phase: PHASE3Status: COMPLETED
Sunitinib Treatment Of Renal Adjuvant Cancer (S-trac): A Randomized Double-blind Phase 3 Study Of Adjuvant Sunitinib Vs. Placebo In Subjects At High Risk Of Recurrent RccClinical TrialClinicalTrials.govPublished Aug 1, 2007Added Apr 16, 2026

This study evaluated the efficacy of adjuvant sunitinib compared to placebo in subjects at high risk of recurrent renal cell carcinoma (RCC). The trial was a randomized double-blind phase 3 study. Not reported in abstract.

Phase: PHASE3Status: COMPLETED
An Open-Label, Multi-Center Extension Study to Characterize the Long-Term Safety and Efficacy of BMS-986165 in Subjects With Moderate-to-Severe Plaque PsoriasisClinical TrialClinicalTrials.govPublished Aug 12, 2019Added Apr 16, 2026

This study evaluated the long-term safety and efficacy of BMS-986165 in subjects with moderate-to-severe plaque psoriasis. The specifics regarding the dosage and duration of treatment were not reported in the abstract. The findings related to efficacy and safety are crucial for understanding the potential long-term implications of this treatment.

Phase: PHASE3Status: ACTIVE_NOT_RECRUITING
An Open-label, Single Arm, Roll-over Study to Provide Continued Treatment With Darolutamide in Participants Who Were Enrolled in Previous Bayer Sponsored StudiesClinical TrialClinicalTrials.govPublished Oct 20, 2020Added Apr 16, 2026

This study evaluated the continued treatment with Darolutamide in participants previously enrolled in Bayer-sponsored studies. The specific outcomes measured and the population characteristics are not detailed in the abstract. The study was conducted as an open-label, single-arm trial.

Phase: PHASE3Status: ACTIVE_NOT_RECRUITING
Semantic Scholar search for NAD+StudySemanticScholarAdded Dec 12, 2025

Not reported in abstract.

Single-cell analysis integrated with RNA-Sequencing uncovers new action of Patchoulol on adipose tissue remodeling in obesity.StudyPubMedAdded Dec 12, 2025

Not reported in abstract.

Nicotinamide riboside enhances the efficacy of gemcitabine and suppresses PDAC premalignant lesions via SIRT3 activation.StudyPubMedAdded Dec 12, 2025

Not reported in abstract.

SMP30 May protect human lens epithelial cells against high glucose-induced oxidative damage by regulating the Keap1/Nrf2/NQO1 pathway.StudyPubMedAdded Dec 12, 2025

Not reported in abstract.

External databases

Helpful external resources for additional structural, pharmacologic, and literature context. These are third-party databases; always cross-check details with primary research.

Community notes

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Community research logs (detail)

No community research logs yet. Use the “Contribute data” button above to share an anonymized summary of your experience.

Anonymous side-effect reporting (detail)

This section describes how anonymous side-effect reports are aggregated into the heatmap above. Reports are anonymous and unverified, and should be read alongside primary safety data.

Use the "Report side effects" button to open a focused popup form. Please keep descriptions neutral and avoid medical language; think in terms of "nausea", "flushing", "vivid dreams", etc.

Librarian Changelog

Every time the Librarian touches this peptide — discovering, refreshing, scoring, or verifying — it logs the action here.

58m agoScoring70%

Scored effects for NAD+

1d agoRefreshai-researcher85%

Refreshed content for NAD+

2d agoRefreshai-researcher85%

Refreshed content for NAD+

3d agoRefreshai-researcher85%

Refreshed content for NAD+

4d agoRefreshai-researcher85%

Refreshed content for NAD+

6d agoRefreshai-researcher85%

Refreshed content for NAD+

May 26Scoring70%

Scored effects for NAD+

May 26Refreshai-researcher85%

Refreshed content for NAD+

Apr 20Refreshdiscovery50%

Refreshed content for NAD+

Apr 20SummarySemanticScholar0%

Auto-summarized study: "Semantic Scholar search for NAD+..."

Apr 17Refreshai-researcher85%

Refreshed content for NAD+

Apr 16Refreshai-researcher85%

Refreshed content for NAD+

Apr 16Refreshai-researcher85%

Refreshed content for NAD+